ID L9KWC6_TUPCH Unreviewed; 783 AA.
AC L9KWC6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Zinc finger protein 791 {ECO:0000313|EMBL:ELW67106.1};
GN ORFNames=TREES_T100006400 {ECO:0000313|EMBL:ELW67106.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW67106.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KB320624; ELW67106.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KWC6; -.
DR InParanoid; L9KWC6; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 3.
DR Gene3D; 6.10.140.140; -; 3.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24381:SF426; ZINC FINGER PROTEIN 846; 1.
DR Pfam; PF01352; KRAB; 3.
DR Pfam; PF00096; zf-C2H2; 7.
DR SMART; SM00349; KRAB; 3.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 3.
DR PROSITE; PS50805; KRAB; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 19..90
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 98..193
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 195..222
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 223..250
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 251..278
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 279..306
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 307..334
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 335..362
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 363..390
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 391..418
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 419..446
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 447..474
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 481..571
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT REGION 623..729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 88384 MW; 76FC2DA8B8C1A5BD CRC64;
MQSVSPFLLH TCEMFQDSVA FEDVVVNFTQ DEWTLLDTSQ KKLYGDVIWE TIENLDFTGR
NWEDEDIEEK YENAIKDLSA VSLSLPPPHT CGMLQDPVAF EDVAVNFTKE EWALLDPAQR
KLYKDVMWET IKNLNTAGLS ASGRCDCELH TGRVGFAGSF TEETLQRCDA GNHQEPGLYS
YLRKHERTHN GEKPYECNKC GKAFKQLYSF RIHEKTHSGE KPYECKECGK AFSHPSSVRM
HEKTHNGDGH YECKQCRKAF SCLSYLQKHE KIHGGNKPYE CKECGKAFIN STCLRIHEMI
HTRQKRYECK QCGKAFRHLQ SLQIHEKTHN GMKPYECKHC GKAYTRSSLL KVHERTHTGE
KPYQCKQCHE AFSCPSAFRK HVRAHTGEKP YQCKICGKTF SSAAHSQIHR RTHTGEKPYE
CKQCGKTFSR SGYFHAHEKI HSGETPYRCQ PCGKAFLRLV NFQRHMIAHT GDGPYKCKDS
VAFEDVIVTF TQEEWALLDP LQRSLYRDVM QETIRNLAST DFCDSVSEDN QSIEDEYTNA
RKILRSYMVE RLYERKEGSQ CGRTFSHVPD MNLNEKTLGV KPQKSSAYEE DFIVHSSLNR
HVITHKGQKL YKHKESFLCK SKVMGSSGRS PHPLQRTSPP SAASAGQSRR SRREDAGTPR
EPATVSVQGP GSRRRRDGWI RGTGCGGPGP PLSPPESAVP ASRGGAGSAA GTPGARPRAN
GELARPGTLH GQLGARSPAC PRAVLGDGTV TRGSPLGFWG FCCEVQWSSS PQITRFPFSF
PNV
//
