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Database: UniProt
Entry: L9L6S8_TUPCH
LinkDB: L9L6S8_TUPCH
Original site: L9L6S8_TUPCH 
ID   L9L6S8_TUPCH            Unreviewed;      1492 AA.
AC   L9L6S8;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   16-JAN-2019, entry version 20.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 1 {ECO:0000313|EMBL:ELW70354.1};
GN   ORFNames=TREES_T100007091 {ECO:0000313|EMBL:ELW70354.1};
OS   Tupaia chinensis (Chinese tree shrew).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX   NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW70354.1};
RN   [1] {ECO:0000313|EMBL:ELW70354.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Zhang G., Fan Y., Yao Y., Huang Z.;
RT   "Genome of the Chinese tree shrew, a rising model animal genetically
RT   related to primates.";
RL   Nat. Commun. 0:0-0(2013).
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DR   EMBL; KB320498; ELW70354.1; -; Genomic_DNA.
DR   InParanoid; L9L6S8; -.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 3.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Receptor {ECO:0000313|EMBL:ELW70354.1};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       66    120       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      157    213       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      220    312       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      318    373       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     1370   1390       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1492 AA;  171477 MW;  2025083D9D597AE9 CRC64;
     MIVGDESADC LFKLCPMNRY SAQKQFWKAA KPGANNTTDA VLLNKLHHAA DLEKKQNETE
     NRKLLGTVIQ YGNVIQLLHL KSNKYLTVNK RLPALLEKNA MRVTLDEAGN EGSWFYIQPF
     YKLRSIGDSV VIGDKVVLNP VNAGQPLHAS SHQLVDNPGC NEGDVVRLFH AEQEKFLTCD
     EHRKKQHVFL RTTGRQSATS ATSSKALWEV EVVQHDPCRG GAGYWNSLFR FKHLATGHYL
     AAEVDPDFEE ECLEFQPSVS MGKSLLVFIG RVDPDQDASR SRLRNAQEKM VYSLVSVPEG
     NDISSIFELD PTTLRGGDSL VPRNSYVRLR HLCTNTWVHS TNIPIDKEEE KPVMLKLEKG
     TITQNERRSV TKLLEDLVYF VTGGTNSGQD VLEVVFSKPN RERQKLMREQ NILKQIFKLL
     QAPFTDCGDG PMLRLEELGD QRHAPFRHIC RLCYRVLRHS QQDYRKNQEY IAKQFGFMQK
     QIGYDVLAED TITALLHNNR KLLEKHITAA EIDTFVSLVR KNREPRFLDY LSDLCVSMNK
     SIPVTQELIC KAVLNPTNAD ILIETKLVLS RFEFEGVSTG ENALEAGEDE EEVWLFWRDS
     NKEIRSKSVR ELAQDAKEGQ KEDRDVLSYY RYQLNLFARM CLDRQYLAIN EISGQLDVDL
     ILRCMSDENL PYDLRASFCR LMLHMHVDRD PQEQVTPVKY ARLWSEIPSE IAIDDYDSSG
     TSKDDIKERF AQTMEFVEEY LRDVVCQRFP FSDKEKNKLT FEVVNLARNL IYFGFYNFSD
     LLRLTKILLA ILDCVHVTTI FPITKITKGE ENKGNNDVEK MKSSNVMRSI HGVGELMTQV
     VLRGGGFLPM TPMAAAPEGN VKQAEPEKED IMVMDTKLKI IEILQVIDAA DARPCQSAVT
     RQSVQGGALD FEHIEEQAEG IFGGRKVYFQ FLLEGNNKSQ KHESTSSYNY RVVKEILIRL
     SKLCVQESAS VRKSRKQQQR LLRNMGAHAV VLELLQIPYE KAEDTKMQEI MRLAHEFLQN
     FCAGNQQNQA LLHKHINLFL NPGILEAVTM QHIFMNNFQL CSEINERVVQ HFVHCIETHG
     RNVQYIKFLQ TIVKAEGKFI KKCQDMVMAE LVNSGEDVLV FYNDRASFQT LIQMMRSERD
     RMDENSPLMY HIHLVELLAV CTEGKNVYTE IKCNSLLPLD DIVRVVTHED CIPEVKIAYI
     NFLNHCYVDT EVEMKEIYTS NHMWKLFENF LVDICRACNN TSDRKHADSI LEKYVTEIVM
     SIVTTFFSSP FSDQSTTLQT RQPVFVQLLQ GVFRVYHCNW LMPSQKASVE GCIRVLSDVA
     KSRAIAIPVD LDSQVNNLFL KSHNIVQKTA MNWRLSARNA ARRDSVLAAS RDYRNIIERL
     QDIVSALEDR LRPLVQAELS VLVDVLHRPE LLFPENTDAR RKCESGGFIC KLIKHTKQLL
     EENEEKLCIK VLQTLREMMT KDRGYGEKLI LLMSRYDHSV INQMRFQNTS YI
//
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