ID L9L7I8_TUPCH Unreviewed; 3071 AA.
AC L9L7I8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Centrosome-associated protein 350 {ECO:0000313|EMBL:ELW70873.1};
GN ORFNames=TREES_T100015803 {ECO:0000313|EMBL:ELW70873.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW70873.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320481; ELW70873.1; -; Genomic_DNA.
DR STRING; 246437.L9L7I8; -.
DR eggNOG; KOG4568; Eukaryota.
DR InParanoid; L9L7I8; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR028750; CEP350/CC187.
DR InterPro; IPR025486; DUF4378.
DR PANTHER; PTHR13958; CENTROSOME-ASSOCIATED PROTEIN 350; 1.
DR PANTHER; PTHR13958:SF4; CENTROSOME-ASSOCIATED PROTEIN 350; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14309; DUF4378; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 2471..2513
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1234..1253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1454..1635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1755..1813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1858..2012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2068..2123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2165..2189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2233..2337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2361..2388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2415..2435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2738..2769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1341..1370
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1670..1754
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2015..2054
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2674..2701
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 439..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..640
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..689
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1188..1224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1460..1490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1514..1531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1553..1567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1619..1635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1755..1780
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1781..1804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1858..1887
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1893..1907
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1940..1975
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1989..2008
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2095..2123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2168..2183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2272..2291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2304..2337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2361..2379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2415..2433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3071 AA; 345734 MW; 4051BEA3D9C28908 CRC64;
MRSSRSKEVP LPNPRNSQSK DTVQDITTSW DALSQTKAAL RHIENKLEVT PASTAMLDSV
MEAKKSSANA TRKISRKEGR YLDDSWVNAP TSKSSKSRKE KSRSPLRATT LESNVKKNNR
VEFRDPLVSY REIHGTPSNL SPSHLESKRV YCIDVTEEKT EGGNRMICHR DERNTPCCDF
ESSQSSVVND TVVRFLNDRP AIDALQNSEC LIKMGVPVST EEELPNRTGG NESNLKSSVI
NVGHDVDPKV LRLADSSPSS TSTSNSQRLD ILKRRQHDVK LEKLKERIRK QWEHSEETNG
RAHNLGHVDH PVMVVNVDSS VTAKVRKVAT APPAPAYRGF NPSETKIRTP DGKVWQEAEF
QNMSRELYRD LALHFADDIA IKEKPVEKSK EKKVVKPVRK IQKVAQLSSP ECKTGNSRLI
STSSWRDGQK LVKKILGPPP RVEQKERRTA SSDRSGKERT TKSAGHIGRA ESDPRLDVSH
RHLPRSSERS RSRAWSENNV KKLAPSLPDN KQEENSALNK DFLPVEIRGI LDDLQLDSAA
QSARQETGEL QSQKSSAPVQ APRSHSPVKR KPDKITASED PPVISKKRHY DTDEVRQYIV
RQQEERKRKQ NEEKKAQKEA TEQKNKRLQE LYRKQKEAFT KVKNVPVSEP SATRRLQETY
SKLLLEKTLL EEPSRQQVTQ ETQARPGYQP SGESDKENKV QERPPSASSS SDMSLSEPPQ
PLARKDLEPT WMQPDRLSPR VQHPQPQPLV GTAGNLLSHL LSLEHVGILH KDFESLLPTR
KNHNVASGPV TFAPQPYLTS PAAHPDALLK PSATQYKSKL DRIEALKATA ASLSSRIESE
AKKLAGANIN YGSVCNTEYD VQRAPQEDGP WAKPVSPPVK EDTEDVFSAR IQKMLGTCVS
HATFDDDLPG VGNLSEFKKL PEMIRPRSAI SSFRMRSPGS KPEGLLAQLC KRQTDSSSSD
LQACSQDKAK LSLGSSIESV SEGPLLSEGS LSEEEGGQDG QPFVKVAEIL KEKEFCAGER
NAYEPIKEFQ KEAEKFLPIF GHISDAQNKG PWEELAKGSP HSVINIFTKS YQLYGKGEKN
NIGGSDLGIQ EDHSSRKPAH DLSSVDATSQ HSSGAHSAAS SRSSSSSKGK KGKKEKREWL
DSFTGNVQNS LLDEEKVQSG TEHGSYQGKK SGTSNKLSVK DSEQTLDTDS TLENLSGHSM
SVSSDKGRSQ KTPASPLSPS SQKLLQFNLP GTSLERSKSS VVMPPTPSGL RTTSAFTDMS
LTASRMPTET GATPGSKRFS PAGLQHRMAA ELSYLNAIEE SVRQLSDVER VRGISLAQQE
TVSLAQIIKA QQQRHERDLA LLKLKAEQEA LECQRQLEET RNQAAQVHAE SLQQVVKSQR
EVTEVLQEAT CKIAAQQTET ARLTTDAARQ ICEMAELTRT HISDAITASG APLAMLYDHQ
RQHLPDFGKH LRARVEPDRK SQSVSLSQSK EETLDSKYQK YSPSYDSYSE SSRYKSHDRR
SSSGSSRQES PSVPSCKENE KKLHGDKMES SIDEQVQTAA DDSLRSDSVP SLPDEKDSTS
IATEYSLKFD ESMTEDEIEE KSFRSLLPSE SHRRFNMEKK RGHHDDSDEE EKSPEKTTLS
SAKELSMPFS GGQDSFSKFT MEMVRQYMKE EEMRAAHQSS LLRLREKALK EKTKAELAWL
EHQKKHLRDK GEDDKMPPLR KKQRGLLLKL QQEKAEIKRL QEANKAARKE RQLILKQQEE
IERIRLTTMK LQEKLKSAGE NKMDSHSDED TKDDKATSPG PTDLETRSPS PISISSSETS
SIMQKLKKMR SRMDEKFLTK REQKLMQRRQ HAEELLEWKR RLDAEEAEIR QMEKQALAAW
DKELIKPKTP KKELEDQRTE QKGKIISEEE SPIPSFSHLN SESSIPEELG SPAVDYGPSE
SLVQEQPGSL DHSVLTEEMV CSQELESSTS PGKHSPPRSC PSVSKQDSSK GSHRTGGQGH
LPIKSHQHCY SWSDESLSMT QSETTSDQSD IEGRIRALKD ELRKRKSVVD QLKKEQKKRQ
KERLKAQEAS LIKQLESYDE FIKKTEAELS RDLETSPTAK PQIKTLSAAS EKPKIKPIPL
HRSETTKNWK SLTESERSRG SLESIAEHVD ASLSVSEKSV SDKSLSAYAK RMIELDSRID
ERFQAPSPIL RSSRNTRAES GDSLENAPSL PLIKELNASH SILDVLDVKV EHSSQQSEIQ
EVEYAKLEGS EIEDAYSKQS GNLEQGDSAE ILSKKDPPVD SANVQTDLVR LATETLHKKE
KMLKDSQSDQ DTDHSPNVQS GKDIPEQKNK KESDLSLSEH LFAPKETSYS EDFEKSSFKK
EISAELYKDD FEVSSLLSLR KDPQSCRDQS QPSRRSRSRA TSFGSDDEIS ECLSEKSLSI
HSSVHSERLL ELKSPTELMK SKERSDVEHE PEVAEPPALA SVSIADELLD FHIGDRVLIG
NVQPGTLRFK GETSFAKGFW AGVELDKPEG NNNGTYDGIV YFVCKEKHGI FAPPQKISHI
PENFNDYVDV NEDEDSYLDE QYQYYNQEQK DTEDLKDREK DAIEYFYEKS LPTTHNIEAL
VDRDRSLKIE TDNIKDTSGV IEAQVHQQSS VDSLISSKED KDLLSDAIEK VSTAAEDDTL
DNTFSEELKK QQQFTEKEEN LYSKVSETLS TPLLDLLTRE KKQLETQLRS SLNEENKSKQ
QLEAVSSLTD NLLQVFVKDT VSQLQQIKKA RNEKIQLSNQ ELLDDDQKKV QPQDLSPNLE
EPSPGIPSCF LRSELEDEKE EISSPDMCPR PESPVFGASG QEELAKRLAE LEISREFLSA
LGDDQDWFDE DFGLSSSHKI QKNKAEETIV PLMAEPKRTP QKPCETLLAV PHTIEEVEIL
VHNAAEELWK WKELGHDLHS ISFPTKLLGS ASKGLDLEST SKRVYKQAVF DLTKEIFEEI
FAEDPNVNQP VWMKPCRINS SYFRRVKNPN NLDEIKNFIA TEVLKLFSLK KEPNHKTDWQ
KMMKFGRKKR DRVDHILVQE LHEEEAQWVN YDEDELCVKM QLADGIFETL IKDTIDVLNQ
ISEKQGRILL V
//
