ID L9LCQ3_TUPCH Unreviewed; 777 AA.
AC L9LCQ3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=SH3 domain-binding protein 4 {ECO:0000313|EMBL:ELW72469.1};
GN ORFNames=TREES_T100009657 {ECO:0000313|EMBL:ELW72469.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW72469.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
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DR EMBL; KB320407; ELW72469.1; -; Genomic_DNA.
DR AlphaFoldDB; L9LCQ3; -.
DR STRING; 246437.L9LCQ3; -.
DR eggNOG; ENOG502QTUW; Eukaryota.
DR InParanoid; L9LCQ3; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.220.30; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR15603:SF3; SH3 DOMAIN-BINDING PROTEIN 4; 1.
DR PANTHER; PTHR15603; SH3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF00791; ZU5; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51145; ZU5; 1.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Membrane {ECO:0000256|ARBA:ARBA00023176};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..83
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 286..423
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
SQ SEQUENCE 777 AA; 85358 MW; E6881D7A8784EE84 CRC64;
MFRLEKQFVP SPSALLADSP TPFGNAKEVI AIRDYCPTNF TTLKFSKGDH LYVLDTSGGE
WWYAHNTTEM GYIPSSHVQP LNYRNSTLSD SGMIDPLPDS PDEVAKELEL LGGWADDGKG
LGKTHSNNPF WNGVQTNPFL NGSLSAAPGV DEPSARRTVD LLLFDAGTAS FMESSSATAN
STGNIFDDLP TTNGLHAEQP VRRDNPFFRS KRSYSLSELS VLQAKSDAPA ASNFFTGLKS
PAPEQFQSRE DFRTAWLNHR KLARSCHDLD LLGQNPGWGQ TQAVETNIVC KLDSSGGAVQ
LPDTSISILV PEGHVAPGET QQISMKALLD PPLELNSDKA SCVSPLLEVK LSTLEVRTFL
ILEMKVSAEV KNDALSKSTV GLQCLRSDSK EGPYVPMPLT YSYGDTVQVQ LDHLEPCMYL
AIVAHGPSIL YPSTVWDFIH KKVTWGRPLA FFCRAEPDSE PERVASVLEK LKEDCNNAEN
KDRKSFQKEL VMSHPQPSVE WLLCPSPSRW ALAVLPLSEQ LLVCCGLAVV PQGKALARGE
LSATREALLL LLSTKQLFVF SLWHVGFLVD TLSCLASSSI IPGGPVRFPG PCLGPHLSPA
SPSLPTGAHP PESLQRVVRP GKGHHLSVSP VGERLGELSS ALLKMDCQGL VVRLIQDFVL
LTTAVEVAQR WRELAEKLAK VSRQQMDAYE SPHRDRNGVV DSEAMWKPAY DFLLTWSHQI
GDSYRDVIQE LHTGLDKMKN PITKRWKHLT GTLILVNSLD VLRAAAFSPA DHDDFVI
//
