ID L9LCV1_TUPCH Unreviewed; 689 AA.
AC L9LCV1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=NKG2D ligand 4 {ECO:0000313|EMBL:ELW72781.1};
GN ORFNames=TREES_T100017529 {ECO:0000313|EMBL:ELW72781.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW72781.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320391; ELW72781.1; -; Genomic_DNA.
DR AlphaFoldDB; L9LCV1; -.
DR STRING; 246437.L9LCV1; -.
DR eggNOG; ENOG502TM6M; Eukaryota.
DR InParanoid; L9LCV1; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IEA:UniProt.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 3.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR PANTHER; PTHR16675:SF64; RETINOIC ACID EARLY TRANSCRIPT 1E; 1.
DR Pfam; PF00129; MHC_I; 3.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 3.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 411..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 647..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..153
FT /note="MHC class I-like antigen recognition-like"
FT /evidence="ECO:0000259|Pfam:PF00129"
FT DOMAIN 161..329
FT /note="MHC class I-like antigen recognition-like"
FT /evidence="ECO:0000259|Pfam:PF00129"
FT DOMAIN 450..619
FT /note="MHC class I-like antigen recognition-like"
FT /evidence="ECO:0000259|Pfam:PF00129"
SQ SEQUENCE 689 AA; 77043 MW; E34BEF8F19956626 CRC64;
MQGSVDREKF LQYDSDSDKA RPVGVLEEEV NTTRAWTELT QTLGEVGREL RILLILSGVT
LEEKEPEGPP SLQAELLCRR EAEQCAGASW QFSINGRTAL LLDAMSMTWT ILSPGARGNK
EEWESDRGLA EYLRKISVGD CNHWLRAVLE LWETTLEPTD THALCYDFTL IPSPRPGQGW
CEVQGQVDWK VFLSYDCGSK VKPISPLGKK VNGTRAWEDQ VIMLRDAGEI FKERLPDIKL
EDDGNRGSLP LQARMSCKCD ASGHTTGAWQ FSFDGQTFLL FDPEKRMWTA VHHTAGGMKE
QWENDREMAM FLEKVSLGDG GSWLEEFLKC WEEVLEPTDT LAVRPGELER VSLRGDTLGK
LSPEFWQILT VTDQGEDRAY PGVGLLTLKR MQVTMWMPTA ATQLLSTMES ASLPLALVIV
YLSSLLLLTE ARMTLGCEFP ERPAEEGDVH SLCLNFTVQS QSRPEQPWCA VQGSVDREKF
LQYDSDSDKA RPVGVLGEEV NTTRAWTELT QTLGEVGREL RSLLSGITLE KKEPEGPLRL
QAELLCRREA EQCAGASWQF SINGRTALLL DAMSMTWTIL SPGARGIKEE WESDRGLAEY
FRKISVGDCN HWLREFLELW ETMLEPTVPP SKTPYTNQSS STTLNAYVVP ITIPCIVIVI
IIIIITCSLA FGCSPGGVTE GEEQAGPLL
//
