ID L9LDB7_TUPCH Unreviewed; 907 AA.
AC L9LDB7;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Protocadherin-11 X-linked {ECO:0000313|EMBL:ELW72931.1};
GN ORFNames=TREES_T100014537 {ECO:0000313|EMBL:ELW72931.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW72931.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- FUNCTION: Potential calcium-dependent cell-adhesion protein.
CC {ECO:0000256|ARBA:ARBA00037723}.
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DR EMBL; KB320381; ELW72931.1; -; Genomic_DNA.
DR eggNOG; ENOG502QPMK; Eukaryota.
DR InParanoid; L9LDB7; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 7.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR InterPro; IPR013585; Protocadherin.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF254; PROTOCADHERIN-11 X-LINKED-RELATED; 1.
DR Pfam; PF00028; Cadherin; 6.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF08374; Protocadherin; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 7.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..907
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004000759"
FT TRANSMEM 813..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..139
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 140..249
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 250..355
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 362..466
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 467..570
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 571..673
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 685..795
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 907 AA; 100121 MW; DAB13EEFCBB123A7 CRC64;
MDLLSGTYIF AVLLACVVFQ SGAQEKNYTV REEMPENVLI GDLLRDLNLS LIPDKSLTSP
MQFKLVYKTG DVPLIRIEES TGEIFTTGAR IDREKLCAGI SMDEHCFYEV EVAVLPDEIF
RLVKIRFLIE DINDNAPLFP ATVINISIPE NSAINSRYSL PAAVDPDVGM NGVQDYQLIK
GQNIFGLDVI ETPEGDKMPQ LIVQKELDRE EKDTYVMKVK VEDGGFPQRS STAILQVSVA
DTNDNHPVFT EKEIEVSIPE NAPVGTSVTQ LHATDADIGE NAKIHFYFSN LVSNIAKRLF
HLNTTTGLIT IKEPLDREES PSHKLLVLAS DGGSTPARAM VLVNVTDIND NVPSIDIRYI
INPINGTVVL SENAPLNTKV ALITVTDKDA DHNGRVTCFT DHEVPFRLRP VFSNQFLLET
AAFLDYESTK EYAIKLLAAD AGKPPLNQSA MLLVKVKDEN DNAPVFTQPS ISLSVPENNF
PGAQLTKISA TDADSGRNAE VSYLLGIDAP SEFNLDRRTG ILTAVKKLDR EKQEKYSFTV
LAKDNGIPPL ITNATVFLTV LDQNDNSPVF THNEYNFYVP ENLPRHGTVG LITVTDPDYG
ENSAVTLSIL DVNDDFTIDP QTGVIRPNIS FDREKQESYT FYVKAEDGGR VSRSSTAKVT
INVVDVNDNK PVFVVPPSNY SFELVLPSTN PGTVVFQVVA VDNDTGINAE LRYSIVGGNT
NGLFTIDQTT GNITLKEKCI SADLGLHRLV VKAKDLGQPD SLFSVIVVNL FVNESVTNAT
LIYELVRKSI EAPVTQNVET TDASSPISDY VKIVVAIVAG AITVILVIFI TAVVRCRQSP
HLKAAQKNKQ NSEWVTPNPE NRQMIMMKKK KKKKKKHAPK NLLLKFVTIE ENKTXXXXXE
CHTRPSH
//
