ID L9UDC4_9GAMM Unreviewed; 453 AA.
AC L9UDC4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Diguanylate cyclase DosC {ECO:0000256|ARBA:ARBA00015125};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
DE AltName: Full=Direct oxygen-sensing cyclase {ECO:0000256|ARBA:ARBA00029839};
GN ORFNames=HALTITAN_0345 {ECO:0000313|EMBL:ELY22707.1};
OS Halomonas titanicae BH1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1204738 {ECO:0000313|EMBL:ELY22707.1, ECO:0000313|Proteomes:UP000011651};
RN [1] {ECO:0000313|EMBL:ELY22707.1, ECO:0000313|Proteomes:UP000011651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BH1 {ECO:0000313|EMBL:ELY22707.1,
RC ECO:0000313|Proteomes:UP000011651};
RX PubMed=23516210;
RA Sanchez-Porro C., de la Haba R.R., Cruz-Hernandez N., Gonzalez J.M.,
RA Reyes-Guirao C., Navarro-Sampedro L., Carballo M., Ventosa A.;
RT "Draft Genome of the Marine Gammaproteobacterium Halomonas titanicae.";
RL Genome Announc. 1:E0008313-E0008313(2013).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY22707.1}.
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DR EMBL; AOPO01000001; ELY22707.1; -; Genomic_DNA.
DR RefSeq; WP_009286155.1; NZ_AOPO01000001.1.
DR AlphaFoldDB; L9UDC4; -.
DR PATRIC; fig|1204738.3.peg.532; -.
DR UniPathway; UPA00599; -.
DR Proteomes; UP000011651; Unassembled WGS sequence.
DR GO; GO:0052621; F:diguanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd14757; GS_EcDosC-like_GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR InterPro; IPR048442; DosC_2nd.
DR InterPro; IPR039435; DosC_GS.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR044398; Globin-sensor_dom.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF21118; DosC_2nd; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF11563; Protoglobin; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF46458; Globin-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022617};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134}.
FT DOMAIN 322..453
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 453 AA; 51342 MW; C2328E428553886C CRC64;
MRYKDKHQLA AEWQALLERT PKPLRQAVET LVEHHGQNFA DHFYRVMLED PHASLFLSNA
QVEQRLHPSM QRWLKAMFAV DHADFESLVE QQEKVGQVHA RIDIPVNLVL SGARQLKQAF
YEQINATFKS PLSPGDASVY VSDHIDMAME IMSHAYSVAS DRNARTEEAY KLFSLTQSIG
DERERQRSAL LNWENALMFA IAAQQDIATL PRLSNSDFGL WYFHKACHAF EGVPEIATIS
RHIQQVDCEW LEVLLHDDAS QRLKALGEIR DAARTVLMLL DNVLERASGL DAGRDSLTRL
LNRKFLSVVL SREIDIARHS EHCFALLMVD IDHFKSINDT HGHDAGDNVL QQVASILDRS
TRGGDYVFRM GGEEFLIVLV NTDHDGSRLF AERLRQSVAK ELMLAGADTL LNVTISVGVT
LHDGHPDYHH SLQRADQALY EAKRGGRDRV VVQ
//
