ID   L9VQ50_9EURY            Unreviewed;       680 AA.
AC   L9VQ50;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   SubName: Full=PAS sensor protein {ECO:0000313|EMBL:ELY39176.1};
GN   ORFNames=C496_15002 {ECO:0000313|EMBL:ELY39176.1};
OS   Natronorubrum tibetense GA33.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natronorubrum.
OX   NCBI_TaxID=1114856 {ECO:0000313|EMBL:ELY39176.1, ECO:0000313|Proteomes:UP000011599};
RN   [1] {ECO:0000313|EMBL:ELY39176.1, ECO:0000313|Proteomes:UP000011599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GA33 {ECO:0000313|EMBL:ELY39176.1,
RC   ECO:0000313|Proteomes:UP000011599};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELY39176.1}.
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DR   EMBL; AOHW01000038; ELY39176.1; -; Genomic_DNA.
DR   RefSeq; WP_006090983.1; NZ_KB913020.1.
DR   AlphaFoldDB; L9VQ50; -.
DR   STRING; 1114856.GCA_000383975_04578; -.
DR   PATRIC; fig|1114856.3.peg.3105; -.
DR   eggNOG; arCOG02278; Archaea.
DR   eggNOG; arCOG06192; Archaea.
DR   OrthoDB; 106505at2157; -.
DR   Proteomes; UP000011599; Unassembled WGS sequence.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR007050; HTH_bacterioopsin.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   Pfam; PF15915; BAT; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF04967; HTH_10; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          163..271
FT                   /note="PAS fold-4"
FT                   /evidence="ECO:0000259|Pfam:PF08448"
FT   DOMAIN          306..446
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|Pfam:PF13185"
FT   DOMAIN          458..611
FT                   /note="Bacterioopsin transcriptional activator GAF and HTH
FT                   associated"
FT                   /evidence="ECO:0000259|Pfam:PF15915"
FT   DOMAIN          618..669
FT                   /note="HTH bat-type"
FT                   /evidence="ECO:0000259|Pfam:PF04967"
SQ   SEQUENCE   680 AA;  74652 MW;  F9CC6E8A55DD0128 CRC64;
     MSHENPSGSI IHITAARASS LESRLNDGTP YAIRTVSVET TLENGLEGGF ESASRDGADA
     QGPVAVVIEH DDPAETKVLL ERCHATDTAA PTIVVPKTGS EALATAALRG YADEYVALGT
     DEDPIERVLE TIRSNRETSA EAARTRPSTR SADRDYHRIL ANELPDEAFV IGEDGTYLEV
     KVRPDAAELY TKPADQLIGE QLQNVFPDDV AAKLAACIDR TLRTDTIQTV EYGAKTTEGD
     RQFEARVVPI DDRIEGQRAV VWLARDITER AKRERELRSR QDQLETLNRI STVVGQVIDT
     LVEAPSRDAI EREVCEQLVD SELYCGAWIA ERTGEGTLAY RTGAGDAETS LQSVEALDAD
     HEWLGQRTVQ TGSAQTEIDV QESETVPEPL QNAAREDDIS SAITVPIDHN DSIYGVLTVL
     ASRDEAFSGD ELTGFELLGE TIGFTIMAVK NRQLLFADTV VELEFRIDGG DTFAFDLSEE
     YGCTCSLEWA GTTSSGRTVQ YVTVDGIDGK TVLEAARDHD SIEGCRLIHD GDTSCTIEMR
     LSESGVRTLA NHGATIRDVS VEDGVGRCVI EVSQDADVRE IAEALTVVYE NTQLIARREV
     DRSVQTAAER RNRILDQLTD RQLTTLRLAY YSGFFDWPRE STGEEIADSM GVTPPTMHQH
     LRKGLKTVLR EFFEAGAETE
//