ID L9VV96_9EURY Unreviewed; 375 AA.
AC L9VV96;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Molybdate/tungstate import ATP-binding protein WtpC {ECO:0000256|ARBA:ARBA00041133};
DE EC=7.3.2.6 {ECO:0000256|ARBA:ARBA00039025};
GN Name=potA {ECO:0000313|EMBL:ELY40946.1};
GN ORFNames=C495_16955 {ECO:0000313|EMBL:ELY40946.1};
OS Natronorubrum sulfidifaciens JCM 14089.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronorubrum.
OX NCBI_TaxID=1230460 {ECO:0000313|EMBL:ELY40946.1, ECO:0000313|Proteomes:UP000011661};
RN [1] {ECO:0000313|EMBL:ELY40946.1, ECO:0000313|Proteomes:UP000011661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14089 {ECO:0000313|EMBL:ELY40946.1,
RC ECO:0000313|Proteomes:UP000011661};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + tungstate(in) = ADP + H(+) + phosphate +
CC tungstate(out); Xref=Rhea:RHEA:35027, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:46502, ChEBI:CHEBI:456216; EC=7.3.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00036926};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (WtpC),
CC two transmembrane proteins (WtpB) and a solute-binding protein (WtpA).
CC {ECO:0000256|ARBA:ARBA00038781}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC Sulfate/tungstate importer (TC 3.A.1.6) family.
CC {ECO:0000256|ARBA:ARBA00038307}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY40946.1}.
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DR EMBL; AOHX01000058; ELY40946.1; -; Genomic_DNA.
DR AlphaFoldDB; L9VV96; -.
DR STRING; 1230460.C495_16955; -.
DR PATRIC; fig|1230460.4.peg.3432; -.
DR eggNOG; arCOG00177; Archaea.
DR OrthoDB; 18368at2157; -.
DR Proteomes; UP000011661; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015408; F:ABC-type ferric iron transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03259; ABC_Carb_Solutes_like; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR015853; ABC_transpr_FbpC.
DR InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013611; Transp-assoc_OB_typ2.
DR PANTHER; PTHR42781; SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA; 1.
DR PANTHER; PTHR42781:SF4; SPERMIDINE_PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF08402; TOBE_2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF50331; MOP-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00022496};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron transport {ECO:0000256|ARBA:ARBA00022496};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011661};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 6..240
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 375 AA; 41161 MW; 2230D4D8767C3541 CRC64;
MTTSAISLEA VTKSFREETV LRDIELEIED GEFCVVLGPS GCGKSTLLKC IAGLIDSDDG
TISLDGRDTA EMSVQDRNLG YVFQEFEETL FPHKTVAENI AFGLEHGEQE RSPEEIDEII
DDMLSLLAIE ETRDDLPSAL SGGQQQRVEL ARQLSRECPI MLFDDPLADL DYKLQKRMEL
EMRSLHADLE STFLYITHNQ DQALKLADKL VVMNHGMIEQ IGTPESVYHN PQTAFVCRFV
GDSNALVTEG VPTDVGDGVV DVETEIGPIT ATTQNGTEKE TGIVIVRPEA VSLDTADCET
TVTGVLEGRT YTGETTEFAL SIDGLDREFY VVVPNDPDIG SVGETMELGW NIDDALYFEK
LSVTDAVTSS DLLGE
//
