ID L9VZ38_9EURY Unreviewed; 403 AA.
AC L9VZ38;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ELY42440.1};
GN ORFNames=C495_15587 {ECO:0000313|EMBL:ELY42440.1};
OS Natronorubrum sulfidifaciens JCM 14089.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronorubrum.
OX NCBI_TaxID=1230460 {ECO:0000313|EMBL:ELY42440.1, ECO:0000313|Proteomes:UP000011661};
RN [1] {ECO:0000313|EMBL:ELY42440.1, ECO:0000313|Proteomes:UP000011661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14089 {ECO:0000313|EMBL:ELY42440.1,
RC ECO:0000313|Proteomes:UP000011661};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY42440.1}.
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DR EMBL; AOHX01000046; ELY42440.1; -; Genomic_DNA.
DR RefSeq; WP_008164516.1; NZ_AOHX01000046.1.
DR AlphaFoldDB; L9VZ38; -.
DR STRING; 1230460.C495_15587; -.
DR PATRIC; fig|1230460.4.peg.3170; -.
DR eggNOG; arCOG00940; Archaea.
DR OrthoDB; 30736at2157; -.
DR Proteomes; UP000011661; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21123; SPASM_MftC-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR027626; Pseudo_SAM_Halo.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04347; pseudo_SAM_Halo; 1.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011661};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 35..245
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 403 AA; 44289 MW; 78B606447F3D41FE CRC64;
MISISKLLCD LDAEGDGLRY DDAEGSSKPQ ITEDKQRRPV VVWNTTRRCN LYCSHCYAGA
DLESAPGEFS TAEAKAFLED LAAYGAPVIL FSGGEPLVRD DLVELVDYAA DLGLRPVLSS
NGTLITREKA IALRDAGLQY AGISVDGLPE RNDRFRGQDG AFDAAVRGIE NCLDVGLKTG
LRYTITDANA PDLEGVVDLL AEKGLDRFCF YHLDYGGRGA EIVDADLTPR EKREAVRRVA
DLTLEYHDRG EEIETLLVGN YADAAFLVEY AREEFGEKQA QVVYDYLERN GGDPTGERVA
DVDYAGNVHL TQFWQGYSLG NVRDRPFGEI WEDESNPLLE AIRNREQHLT GKCADCQYQS
ICRGGSRLRA LATTGDLFAP DPQCYLSDVE VRGTDPSVGA SAD
//
