ID L9W597_9EURY Unreviewed; 541 AA.
AC L9W597;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Xanthine/uracil/vitamin C permease {ECO:0000313|EMBL:ELY44512.1};
GN ORFNames=C495_11444 {ECO:0000313|EMBL:ELY44512.1};
OS Natronorubrum sulfidifaciens JCM 14089.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronorubrum.
OX NCBI_TaxID=1230460 {ECO:0000313|EMBL:ELY44512.1, ECO:0000313|Proteomes:UP000011661};
RN [1] {ECO:0000313|EMBL:ELY44512.1, ECO:0000313|Proteomes:UP000011661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14089 {ECO:0000313|EMBL:ELY44512.1,
RC ECO:0000313|Proteomes:UP000011661};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY44512.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOHX01000039; ELY44512.1; -; Genomic_DNA.
DR RefSeq; WP_008163001.1; NZ_AOHX01000039.1.
DR AlphaFoldDB; L9W597; -.
DR STRING; 1230460.C495_11444; -.
DR PATRIC; fig|1230460.4.peg.2323; -.
DR eggNOG; arCOG02805; Archaea.
DR OrthoDB; 76842at2157; -.
DR Proteomes; UP000011661; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR11119:SF3; LD30822P; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011661};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 56561 MW; 4E3AAC1EEC7761F6 CRC64;
MTDEGDKHAD RDAGDGVDRD VSDHIEYGID DRPPLGESTV LGIQHYLTMV GANIAVPLIL
ASAMGMPGDV TARFIGTFFV VSGIATLAQT TFGNRYPIVQ GAPFSMLAPA LAIIAVVTAG
GVGGAGTDWQ AALVQLQGAI IVAATVQVLM GYFGLVGKLQ RFLSPVVVAP TIALIGLALF
DAPQITSVDQ SWWLLGLTLV LIVLFSQYLD IKHKAFRLYP VILAIAIAWI AAALLSVAGV
LGSGHPGHVP LGDVTETSAV LPIYPFQWGT PEITTAFVIG MFAGVLASIV ESIGDYYAVA
NMTGSGAPSE KRINHGIGME GLMNVFSGIM GTGGSTSYSE NVGAIGLTGV ASRYVVQIGA
AIMLVVGFIG YFGQLIATIP DPIVGGLFIA MFAQIVAVGI SNLKHVDLDS SRNVFVIGFA
LFVGLAIPEY MANFGSTLEF RDAVALEATL APLLEADAVA GTAIAGTLEA AIQAFVDTVF
IIGSTGMAVG GLAALVLDNT IPGSREERGL AEWDRLTEDD AEFETFWERW TGSDADTDRR
T
//
