ID L9W719_9EURY Unreviewed; 787 AA.
AC L9W719;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=DEAD/DEAH box helicase domain-containing protein {ECO:0000313|EMBL:ELY45269.1};
GN ORFNames=C495_08355 {ECO:0000313|EMBL:ELY45269.1};
OS Natronorubrum sulfidifaciens JCM 14089.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronorubrum.
OX NCBI_TaxID=1230460 {ECO:0000313|EMBL:ELY45269.1, ECO:0000313|Proteomes:UP000011661};
RN [1] {ECO:0000313|EMBL:ELY45269.1, ECO:0000313|Proteomes:UP000011661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14089 {ECO:0000313|EMBL:ELY45269.1,
RC ECO:0000313|Proteomes:UP000011661};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY45269.1}.
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DR EMBL; AOHX01000036; ELY45269.1; -; Genomic_DNA.
DR RefSeq; WP_008161852.1; NZ_AOHX01000036.1.
DR AlphaFoldDB; L9W719; -.
DR STRING; 1230460.C495_08355; -.
DR PATRIC; fig|1230460.4.peg.1689; -.
DR eggNOG; arCOG00553; Archaea.
DR OrthoDB; 371946at2157; -.
DR Proteomes; UP000011661; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELY45269.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011661}.
FT DOMAIN 28..197
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 232..427
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 787 AA; 86549 MW; C05F741C77486027 CRC64;
MEVAEVLPEF ADAFAFEEFN RMQREALPGL LESDENVVAS APTASGKTAL AELAICKALS
DGGTALFIAP LRALTNEKED DWERFENLDY SVYVVTGERD LNPRRARRAD ILVMTPEKLD
SATRKHDSRR YDFVTDIDVC VIDEVHLLDA DRRGSVLEVT ISRLRRLCAP RVVALSATMP
NVDDVAAWLD APEQTTFEFG DEYRPVDLHA GVKTYTHGEN SFADKYRRLY RALDIAEPHL
REDGQALVFV SSRQDTVRAA EKARDEIAKR DVPMTARHDF HDYDFHDEKE DLENETLSKS
VTDGVAFHHA GLSKNDRDFV EKWFKKGAIE LLFSTSTLAW GVNLPARCVV IRDTKHHDPL
EGEVDMSPLD VLQMLGRAGR PGYDDVGYGW VVCDGADADK YRQLLRDGKE IESRLAETLE
THLNAEIAMG TIADLEDVMD WLETTFYYVR GQSKPDAYDF PNLRQRVRDC LEGLVDRGFV
ETGPELSIEA TPRGVLASKY YLRLETAATF AELCDRVEGG ESLEPEDILE AVATAGEFDS
VSARQSERDA INAVLVGQET GDLEAGQRKV LAILRGAASG STPSELRSDA WVIRRNATRL
ISALGAFLDR LTDPHAANLA RRVEAQIENG VAEDAVGLTA IDGVGPGRAS KLATEGISTP
EDVVAAGLEG LIDAGLSEGV AERVYEGAQS LPVLEIDWGA FPESIATGEN DVREVTVRNV
GEPARAGIRV TVNGVEMSST STYLRDTETL PVGVFGADAD ELEFTVSVAI PEEPLVPLEE
SRTVDVV
//
