ID L9WNQ0_9EURY Unreviewed; 492 AA.
AC L9WNQ0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Thymidine phosphorylase {ECO:0000313|EMBL:ELY50992.1};
DE EC=2.4.2.4 {ECO:0000313|EMBL:ELY50992.1};
GN ORFNames=C493_18451 {ECO:0000313|EMBL:ELY50992.1};
OS Natronolimnohabitans innermongolicus JCM 12255.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronolimnohabitans.
OX NCBI_TaxID=1227499 {ECO:0000313|EMBL:ELY50992.1, ECO:0000313|Proteomes:UP000011602};
RN [1] {ECO:0000313|EMBL:ELY50992.1, ECO:0000313|Proteomes:UP000011602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 12255 {ECO:0000313|EMBL:ELY50992.1,
RC ECO:0000313|Proteomes:UP000011602};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY50992.1}.
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DR EMBL; AOHZ01000084; ELY50992.1; -; Genomic_DNA.
DR RefSeq; WP_007260948.1; NZ_AOHZ01000084.1.
DR AlphaFoldDB; L9WNQ0; -.
DR STRING; 1227499.C493_18451; -.
DR PATRIC; fig|1227499.3.peg.3801; -.
DR eggNOG; arCOG02013; Archaea.
DR OrthoDB; 9827at2157; -.
DR Proteomes; UP000011602; Unassembled WGS sequence.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0009032; F:thymidine phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0046125; P:pyrimidine deoxyribonucleoside metabolic process; IEA:InterPro.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR Gene3D; 1.20.970.50; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR017713; AMP_phosphorylase.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR017872; Pyrmidine_PPase_CS.
DR InterPro; IPR013466; Thymidine/AMP_Pase.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR03327; AMP_phos; 1.
DR NCBIfam; TIGR02645; ARCH_P_rylase; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
DR PROSITE; PS00647; THYMID_PHOSPHORYLASE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:ELY50992.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011602};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ELY50992.1}.
FT DOMAIN 413..480
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
FT COILED 84..111
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 492 AA; 52467 MW; FDF1754B0D1F6022 CRC64;
MQLEATSIDI GTSRPLVLLN TIDAEELGAH PLDRVLLSWA GETMTGIVKR TDELVEPGTV
GVTEPLHHVH GAVGVTLAGT PPSVRCVRKK LDDVELERAE LERIVRDIHE HRLSDVELSA
FVSAVYTNGL SLAETKHLTE AMGDIGQRLQ WDRPVVADKH SIGGVAGNCV TPIMVAIVTA
AGVTMPKTSS RAVTSPAGTA DVMEVLSNVE FSIAEIERIV EETNGCLVWG GGVDLSPVDD
EIIRAENPLS IDPDGLLMAS VLSKKQSAGS SHVVIDIPYG EGAKVESLVA ARGLADDFRR
VGDYLEMDVS CAITHGTDPI GRGVGPVLEA RDVLAVLEGD GPESLRLKSL RLAEMLLEHC
DVDAAATEIL ESGRALEQFR SIVAAQGGDP DVESTDLEPG EESTTVRVDR AGVTSRVDNR
TLSDLARRAG APRDSGAGLV VHRTVGDEVE PGDRLYTIHA ETESKLEEAV SFAEGLEPVR
VRSKADALVE RR
//
