ID L9X328_9EURY Unreviewed; 689 AA.
AC L9X328;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:ELY55886.1};
GN ORFNames=C493_10423 {ECO:0000313|EMBL:ELY55886.1};
OS Natronolimnohabitans innermongolicus JCM 12255.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronolimnohabitans.
OX NCBI_TaxID=1227499 {ECO:0000313|EMBL:ELY55886.1, ECO:0000313|Proteomes:UP000011602};
RN [1] {ECO:0000313|EMBL:ELY55886.1, ECO:0000313|Proteomes:UP000011602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 12255 {ECO:0000313|EMBL:ELY55886.1,
RC ECO:0000313|Proteomes:UP000011602};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY55886.1}.
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DR EMBL; AOHZ01000047; ELY55886.1; -; Genomic_DNA.
DR RefSeq; WP_007259367.1; NZ_AOHZ01000047.1.
DR AlphaFoldDB; L9X328; -.
DR STRING; 1227499.C493_10423; -.
DR PATRIC; fig|1227499.3.peg.2114; -.
DR eggNOG; arCOG00554; Archaea.
DR OrthoDB; 39583at2157; -.
DR Proteomes; UP000011602; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47961:SF1; ATP-DEPENDENT HELICASE MJ1401-RELATED; 1.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELY55886.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011602}.
FT DOMAIN 236..415
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 435..591
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 43..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 689 AA; 77313 MW; D00AC95C0E014125 CRC64;
MSKQVQDVET IFCHQTGDDY LVVVERDGKR LFRAKLGLSE TSAGPRPAKF RLKDGSSEEP
RQPDEFVELA RRAQRIRISE QTAPEKRREL TEMLSGYQLE EKTKAVRTCR YCASAGRYSP
ITTETAIKDD NDWICRDCAR QELERQLSYA GSSGRVTGAA KERLEDLMLE VQELDRIINL
LKGELDPDLT KFDTISATTD EVDPVRVDSL SLHPGLQNLL EDRFETLLPV QSLAVENGLF
DGDDQMVVSA TATGKTLVGE MTGIDRVLNG KGKMLFLVPL VALANQKHED FEDEYGHLVD
VSIRVGASRI TDDGNQFDPN ADVIVGTYEG IDHALRTGKD MGDIGTVVID EVHTLKEEER
GHRLDGLISR LKYTCEQRAK QRDDYQGAQW VYLSATVGNP EELAASLEST LIEFEERPVP
IERHVTFADG QEKVRIENKL VRREFDTESS KGYRGQTIIF TNSRRRCHEI SRKLDYSAAP
YHAGLDYKRR KQVERQFGEQ ELAAVVTTAA LAAGVDFPAS QVVFDSLAMG IEWLSVQEFH
QMLGRAGRPD YHDEGKVYVL VEPDTAYHNS MEMTEDEVAF KLLKGEMESV MTHYDEGAAV
EETLANVTVG GKAAKSLNDR MIGDVPTKHA LGKLLQYEFI DGFEPTPLGQ VVTQHFLEPG
EAFTLVDGIR KDAHPYELVA DIELRETEL
//
