ID L9X9R6_9EURY Unreviewed; 245 AA.
AC L9X9R6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:ELY57378.1};
GN ORFNames=C493_07831 {ECO:0000313|EMBL:ELY57378.1};
OS Natronolimnohabitans innermongolicus JCM 12255.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronolimnohabitans.
OX NCBI_TaxID=1227499 {ECO:0000313|EMBL:ELY57378.1, ECO:0000313|Proteomes:UP000011602};
RN [1] {ECO:0000313|EMBL:ELY57378.1, ECO:0000313|Proteomes:UP000011602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 12255 {ECO:0000313|EMBL:ELY57378.1,
RC ECO:0000313|Proteomes:UP000011602};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY57378.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOHZ01000041; ELY57378.1; -; Genomic_DNA.
DR AlphaFoldDB; L9X9R6; -.
DR STRING; 1227499.C493_07831; -.
DR eggNOG; arCOG02646; Archaea.
DR Proteomes; UP000011602; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR47506:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR LMRA; 1.
DR PANTHER; PTHR47506; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000011602};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 5..65
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 28..47
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 195..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 27891 MW; C340D8877E1773A7 CRC64;
MTDQTETTDE LMAATYTALC EHGYASLRMQ DIADESTKSK ATLHYHYESK QDLLYALFDH
LTDSFAELIE TLEGETAADR LLSLAEAYLS PGEEDDRRQF RTALLEIKAQ APYDGRFRAE
LTAFDRLLYD RIRSLIEEGQ AEGTIRADVD PDESAEFVIT VLNGAQVRHV AVDYDPGRTY
ATLETHVREQ LLAEGADAEF ARETDRRDER GTEQTRDEDD QMRDRNGAKE RARERTRRNG
EGGPE
//
