ID L9XPT1_9EURY Unreviewed; 425 AA.
AC L9XPT1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN ORFNames=C489_18931 {ECO:0000313|EMBL:ELY63512.1};
OS Natrinema versiforme JCM 10478.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=1227496 {ECO:0000313|EMBL:ELY63512.1, ECO:0000313|Proteomes:UP000011632};
RN [1] {ECO:0000313|EMBL:ELY63512.1, ECO:0000313|Proteomes:UP000011632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10478 {ECO:0000313|EMBL:ELY63512.1,
RC ECO:0000313|Proteomes:UP000011632};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC Rule:MF_01407}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY63512.1}.
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DR EMBL; AOID01000060; ELY63512.1; -; Genomic_DNA.
DR RefSeq; WP_006432877.1; NZ_AOID01000060.1.
DR AlphaFoldDB; L9XPT1; -.
DR STRING; 1227496.C489_18931; -.
DR PATRIC; fig|1227496.3.peg.3798; -.
DR OrthoDB; 195574at2157; -.
DR Proteomes; UP000011632; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01407};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW Rule:MF_01407};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01407}.
FT DOMAIN 76..237
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 330..415
FT /note="Cdc6 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01074"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 88..92
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 236
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 248
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 425 AA; 47949 MW; 0ACC4FD22F94E097 CRC64;
MAEEPSQLSD FDGRYEDPAD DPLFDFDEDD PDRANIFARK ELLKVGYVPE SGRIVGRDGE
IKAVAAELRP IVRGDPPNNV IIYGKTGTGK SLVARHVTER ARRAAESNGV SVGTVYVDCA
QHNTQTRVAR TVTRSLNETD ETDFDIPRAG IGSGEYYDYL WEILDTAYES VIIILDEVDR
LDDDDILMQL SRARESGKAD CHLGVIAVSN KIEYRDQLNE RVKSSLREEE FVFQPYDANQ
LREIMKHRRD AFHDGVLSDD VIPLTAALAA QEHGDARKAI EILRHAGELA ERENVDTVVE
EHVRDAQEWA EIDRFEELLR GSTTQVKFIL YSLALLTEEN PNEDGFSTNR IYERYQATTE
KADAKTLSEH RVYELLKEQA FLGVVESTRT GGGRGEGSYL EHRLVQDTGI VLKSVLRDSR
LEDLA
//
