ID L9XWT5_9EURY Unreviewed; 791 AA.
AC L9XWT5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=DEAD/DEAH box helicase domain protein {ECO:0000313|EMBL:ELY65891.1};
GN ORFNames=C489_13558 {ECO:0000313|EMBL:ELY65891.1};
OS Natrinema versiforme JCM 10478.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=1227496 {ECO:0000313|EMBL:ELY65891.1, ECO:0000313|Proteomes:UP000011632};
RN [1] {ECO:0000313|EMBL:ELY65891.1, ECO:0000313|Proteomes:UP000011632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10478 {ECO:0000313|EMBL:ELY65891.1,
RC ECO:0000313|Proteomes:UP000011632};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY65891.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOID01000041; ELY65891.1; -; Genomic_DNA.
DR RefSeq; WP_006431800.1; NZ_AOID01000041.1.
DR AlphaFoldDB; L9XWT5; -.
DR STRING; 1227496.C489_13558; -.
DR PATRIC; fig|1227496.3.peg.2719; -.
DR OrthoDB; 371946at2157; -.
DR Proteomes; UP000011632; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd17921; DEXHc_Ski2; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELY65891.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 28..197
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 232..424
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 791 AA; 86462 MW; AC4CD99A32696B77 CRC64;
MEVAEVLPEF ADAFAFEEFN RMQREALPAL LESEDNVVAS APTASGKTAL AELAICKALA
DGGTALFIAP MRALTNEKED DWDRFEELDY SVYVVTGERD LNPRRARRAD ILVMTPEKLD
SATRKHDSRR YDFVTDIDVC VIDEVHLLDA DRRGSVLEVT ISRLRRLCDP RVVALSATMP
NIGDVAAWLD APEETTFEFG EEYRPVELNA GVKTYTHGDN SFADKYRRLY RALDLAEPHL
REDGQSLVFV SSRQDTVQAA KKARDEIAER DIPMGARGDY DFHTDSKELD DGTLRKSVLD
GVAFHHAGLS KNDRDLVEEW FKAGHIELLF STSTLAWGVN LPARCVVIRD TKHHDPLEGE
VDMSPLDVLQ MLGRAGRPGY DDVGYGWVVC DTAEADKYRR LLRDGKEIES RLAESLETHL
NAEIAMGTIT DLEDVMDWLE TTFYYVRGQS KPDEYDFPNL RQRVRDCLEG LVDRGFVETG
EDLSIEATPR GVLTSKYYLR LDTAARFAAL CDRVGGEDGG SASGDELTTG DILEAVATAA
EFDSVSSRQD ERDAISAVLV GEDTADLEAG ERKVLAILRS AASGTTPSEL RSDAWVIRQN
ATRLLSALGA FLDRFVGPHA ANLARRVEAR IENGVAEDAV GLTAIDGVGS GRASKLATEG
LSTPGDVVDA GVAGLVDAGL TEGVAEGVSE GAQSLPAIEI EWGQFPETVA TGENEVCEVT
VRNVGEPARA GVRVTVNGVE MTSTNTYLRD AETLPVGVFG ADADELEFTV SVAFPEEPLV
PITDTRIVRV E
//
