ID   L9Y067_9EURY            Unreviewed;       703 AA.
AC   L9Y067;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=PAS sensor protein {ECO:0000313|EMBL:ELY67102.1};
GN   ORFNames=C489_11580 {ECO:0000313|EMBL:ELY67102.1};
OS   Natrinema versiforme JCM 10478.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrinema.
OX   NCBI_TaxID=1227496 {ECO:0000313|EMBL:ELY67102.1, ECO:0000313|Proteomes:UP000011632};
RN   [1] {ECO:0000313|EMBL:ELY67102.1, ECO:0000313|Proteomes:UP000011632}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10478 {ECO:0000313|EMBL:ELY67102.1,
RC   ECO:0000313|Proteomes:UP000011632};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELY67102.1}.
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DR   EMBL; AOID01000031; ELY67102.1; -; Genomic_DNA.
DR   RefSeq; WP_006431399.1; NZ_AOID01000031.1.
DR   AlphaFoldDB; L9Y067; -.
DR   STRING; 1227496.C489_11580; -.
DR   PATRIC; fig|1227496.3.peg.2340; -.
DR   OrthoDB; 106505at2157; -.
DR   Proteomes; UP000011632; Unassembled WGS sequence.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR007050; HTH_bacterioopsin.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   Pfam; PF15915; BAT; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF04967; HTH_10; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          187..295
FT                   /note="PAS fold-4"
FT                   /evidence="ECO:0000259|Pfam:PF08448"
FT   DOMAIN          332..470
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|Pfam:PF13185"
FT   DOMAIN          482..635
FT                   /note="Bacterioopsin transcriptional activator GAF and HTH
FT                   associated"
FT                   /evidence="ECO:0000259|Pfam:PF15915"
FT   DOMAIN          642..691
FT                   /note="HTH bat-type"
FT                   /evidence="ECO:0000259|Pfam:PF04967"
FT   REGION          38..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   703 AA;  77262 MW;  8CC6511705C88FB9 CRC64;
     MTGTDRSGSI VVVTDTRAGE SYLRPRLETA TEYGVRTVPA SGDLEGALGS APPSENGDGD
     GAIDVNPAGS ETDVFDAGET TAAAASSADE EAVSTPRAVV LELDCPGEIQ TVLQRVHAVG
     PTVPTIVAPR EGSERLATVA LRADATEYVP TERDEDPIDR IVSTIRSRPQ PPSDGDDGRY
     RRILANELPD EAFVIGEDGT YLEAKVRPDS ADLYSMTVDD LPGTRLEAAF PDQVAAKLQD
     CLDRAIRTDD VQSVEYDVKT TEGRRRFEGR VVPIGQRIQG RRAVVWLARD ITERVQRERK
     LRSRQDQLET LNRINAVVRQ VIETLVEAPA RDAIEDEVCE QLVDSELYCG SWIAERTGDG
     RLSVRTGAGE AETYLDRVRD LEGGAERPVA RAIRTGEIQT TNRILEAETI PEPLQEAARE
     DDVRSAIAVP ITHEDATYGV LTVLASRDDA FSERERAGFR LLGETIGFTI MAVKNRQLLF
     ADTVVELEFR IDGGDTFAFD LSEEYGCPCS LEWAGTTANG RTFQYVTIDG LDGETVCKAA
     SDHESVEECR LIHDGEESCT IEMRLSESGV RTLTKHGATI RDVVVEDGVG TCLVEVSQDA
     DVREIAEALT RIYENTELVA RREVDRPVRT AAQRRSRILD RLTDRQLTTL RLAYYGGFFE
     WPRESTGEEI AESMDISPPT MHQHLRKGLE AILGEFFEGG GHS
//