ID L9Y1Q4_9EURY Unreviewed; 546 AA.
AC L9Y1Q4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=TrkA-N domain protein {ECO:0000313|EMBL:ELY67994.1};
GN ORFNames=C489_08320 {ECO:0000313|EMBL:ELY67994.1};
OS Natrinema versiforme JCM 10478.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=1227496 {ECO:0000313|EMBL:ELY67994.1, ECO:0000313|Proteomes:UP000011632};
RN [1] {ECO:0000313|EMBL:ELY67994.1, ECO:0000313|Proteomes:UP000011632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10478 {ECO:0000313|EMBL:ELY67994.1,
RC ECO:0000313|Proteomes:UP000011632};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY67994.1}.
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DR EMBL; AOID01000026; ELY67994.1; -; Genomic_DNA.
DR RefSeq; WP_006430733.1; NZ_AOID01000026.1.
DR AlphaFoldDB; L9Y1Q4; -.
DR STRING; 1227496.C489_08320; -.
DR PATRIC; fig|1227496.3.peg.1682; -.
DR OrthoDB; 43518at2157; -.
DR Proteomes; UP000011632; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833:SF9; POTASSIUM CHANNEL PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..234
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 248..332
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 341..455
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 462..546
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 546 AA; 58491 MW; A64EBFC6EDD81599 CRC64;
MALWRSRRAG YYLALVAATT VVSTLLYNYG MATWENDPQP LYRSLEIVFQ TYTTTGYGED
AGWATPQMNL LMIGLQLTGI GLILTGVDIF AVPWLRDALA TTPPAAVPDL EDHVIICAYT
SRVEAFIDEL ESRGQEYVVI EPDEGTATEL HETDRRVVHG DPESTDVLEN AGIERATAVV
ADSADDTNAS IVLSAREANP DVRIVTLVED QRLGEYHRIA GADEVLSPRQ LLGESLAHRV
PTAVTTAVDE GVEIGNGLEL VELSIAEGSN LCQRTAEEIR LPERFGVDGI GAWLDGEFES
PIPPDRELDT GTRLLVAGEA DRIDALRSEA ASTIQPFSAQ HVVIAGYGEA GAAAGAALAE
TNSRVTVLDS ADKEDVDVIG DARDPAAIRE AGIDDASAVI VTLDDDTTAI FATLVARDLN
PSVDIVVRAN DAESEQKLYR AGADYVQSLA TVSGRMLAST VFEDEDVLAV DRQIDVVKLP
AGRLAGRTVT DADVRSRTGC TVLAVVRDGE TIVEFDPASF VLEDDDAVVL AGTDESVQSF
ESQFLA
//
