ID LPTD_SODGM Reviewed; 780 AA.
AC Q2NVX3;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN OrderedLocusNames=SG0427;
OS Sodalis glossinidius (strain morsitans).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=343509;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=morsitans;
RX PubMed=16365377; DOI=10.1101/gr.4106106;
RA Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA Aksoy S.;
RT "Massive genome erosion and functional adaptations provide insights into
RT the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL Genome Res. 16:149-156(2006).
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000255|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
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DR EMBL; AP008232; BAE73702.1; -; Genomic_DNA.
DR RefSeq; WP_011410290.1; NZ_LN854557.1.
DR AlphaFoldDB; Q2NVX3; -.
DR SMR; Q2NVX3; -.
DR STRING; 343509.SG0427; -.
DR KEGG; sgl:SG0427; -.
DR eggNOG; COG1452; Bacteria.
DR HOGENOM; CLU_009039_2_0_6; -.
DR OrthoDB; 9760225at2; -.
DR BioCyc; SGLO343509:SGP1_RS03890-MONOMER; -.
DR Proteomes; UP000001932; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT CHAIN 25..780
FT /note="LPS-assembly protein LptD"
FT /id="PRO_0000281639"
SQ SEQUENCE 780 AA; 88444 MW; B22967389586D83C CRC64;
MKKRLPTLLA SLIGSALYSQ QALADLADQC LLGVPAYTKP LVSGDANSLP VHIQADKAAA
NYPEHALFSG NVYIEQGNST LTADEVQLTQ RQEQNNAPLR TATATGNVNY SSNEIKLQGP
KAWSNLNTKD TDVYQGNYQI VGRQGRGDAD TMKQRGDNRY TVLENGSFTS CLPGDDSWSV
VGSEVIHDRE EQVAEIWNAR FKIGKVPVFY SPYLQIPVGD KRRSGFLIPN AKYGSNNGFE
FSAPYYLNLA PNYDATIMPN YMSKRGTQIQ TEFRYHTTPG EGLVEFDWLP KDRVYSSEHA
SDGDSDRWLL YWRHNGVMDQ VWRFNVDYTK VSDSNYFDDL DSKYGSTTDG YATQKFSFGY
ADENWDTALS YKQFQVFDTN SSDAYRTAPQ LDVTYYKNDV GPFDFKVFSQ AAKFTNVNNS
YPEATRLHIE PTLNLPLANR WGSLNTEAKL MATHYQQENI DEYNENTGTG RHLKGSVNRV
LPQFKTDGKM VFERDMDYAP DYTQTLEPRL QYLYVPYRNQ NDIGVYDSTI LQTDYSGLFR
DRTYSGLDRI SSANQLAGGV TTRIYDDQRA ERFNASVGQI YYFSRPRTGD ITGTWDNYDN
TGSVVWAGDS YWRISNQWGI RGGLQYDSRL NSVALGDAVL EYRRDENRIL QLNYHYASPQ
YIEQMLSDIS HTGYQQGISQ VGVTGSWQLV DRWSLVGAYY YDTKANQPAD QLVGLQYNTC
CWAINVGYER KITGWNSTDS SSQYDNKVSF NIELRGLSSN YGLGTDKMLA SGILPYQRAF
//
