ID LRC3B_BOVIN Reviewed; 259 AA.
AC A6H789;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Leucine-rich repeat-containing protein 3B;
DE Flags: Precursor;
GN Name=LRRC3B;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hypothalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the LRRC3 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC146155; AAI46156.1; -; mRNA.
DR RefSeq; NP_001092865.1; NM_001099395.1.
DR AlphaFoldDB; A6H789; -.
DR SMR; A6H789; -.
DR STRING; 9913.ENSBTAP00000044315; -.
DR GlyCosmos; A6H789; 2 sites, No reported glycans.
DR PaxDb; 9913-ENSBTAP00000044315; -.
DR Ensembl; ENSBTAT00000047081.2; ENSBTAP00000044315.1; ENSBTAG00000033140.2.
DR GeneID; 783571; -.
DR KEGG; bta:783571; -.
DR CTD; 116135; -.
DR VEuPathDB; HostDB:ENSBTAG00000033140; -.
DR VGNC; VGNC:52799; LRRC3B.
DR eggNOG; KOG4237; Eukaryota.
DR GeneTree; ENSGT00940000157780; -.
DR HOGENOM; CLU_064640_0_0_1; -.
DR InParanoid; A6H789; -.
DR OMA; ANSVICK; -.
DR OrthoDB; 5397338at2759; -.
DR TreeFam; TF327070; -.
DR Proteomes; UP000009136; Chromosome 27.
DR Bgee; ENSBTAG00000033140; Expressed in granulosa cell and 95 other cell types or tissues.
DR GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00369; LRR_TYP; 3.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 3.
PE 2: Evidence at transcript level;
KW Glycoprotein; Leucine-rich repeat; Membrane; Reference proteome; Repeat;
KW Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..33
FT /evidence="ECO:0000255"
FT CHAIN 34..259
FT /note="Leucine-rich repeat-containing protein 3B"
FT /id="PRO_0000345965"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 34..64
FT /note="LRRNT"
FT REPEAT 65..86
FT /note="LRR 1"
FT REPEAT 89..110
FT /note="LRR 2"
FT REPEAT 114..135
FT /note="LRR 3"
FT DOMAIN 145..197
FT /note="LRRCT"
FT CARBOHYD 47
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 94
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 259 AA; 29303 MW; B085ECF266EA740A CRC64;
MNLVDLWLTR SLSMCLLLQS FVLMILCFHS ASMCPKGCLC SSSGGLNVTC SNANLKEIPR
DLPPETVLLY LDSNQITSIP NEIFKDLHQL RVLNLSKNGI EFIDEHAFKG VAETLQTLDL
SDNRIQSVHK NAFNNLKARA RIANNPWHCD CTLQQVLRSM VSNHETAHNV ICKTSVLDEH
AGRPFLNAAN DADLCNLPKK TTDYAMLVTM FGWFTMVISY VVYYVRQNQE DARRHLEYLK
SLPSRQKKAD EPDDISTVV
//
