ID LUXP_VIBPA Reviewed; 365 AA.
AC Q87GU4;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Autoinducer 2-binding periplasmic protein LuxP;
DE Flags: Precursor;
GN Name=luxP; OrderedLocusNames=VPA1221;
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633;
RX PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
CC -!- FUNCTION: Binds to the signaling molecule autoinducer 2 (AI-2), a
CC furanosyl borate diester, (3a-methyl-5,6-dihydrofuro-
CC [2,3d][1,3,2]dioxaborole-2,2,6,6a-tetraol). This complex then interacts
CC with the LuxQ sensor protein (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC {ECO:0000305}.
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DR EMBL; BA000032; BAC62564.1; -; Genomic_DNA.
DR RefSeq; NP_800731.1; NC_004605.1.
DR RefSeq; WP_005463467.1; NC_004605.1.
DR AlphaFoldDB; Q87GU4; -.
DR SMR; Q87GU4; -.
DR GeneID; 1191917; -.
DR KEGG; vpa:VPA1221; -.
DR PATRIC; fig|223926.6.peg.4149; -.
DR eggNOG; COG1879; Bacteria.
DR HOGENOM; CLU_064743_1_0_6; -.
DR Proteomes; UP000002493; Chromosome 2.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProt.
DR CDD; cd06303; PBP1_LuxPQ_Quorum_Sensing; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR PANTHER; PTHR46847; D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED; 1.
DR PANTHER; PTHR46847:SF1; D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 3: Inferred from homology;
KW Periplasm; Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..365
FT /note="Autoinducer 2-binding periplasmic protein LuxP"
FT /id="PRO_0000031727"
SQ SEQUENCE 365 AA; 41340 MW; 24B6D1192B0D6D84 CRC64;
MNKALVLSLI SIAGMSPASQ ASQVLNGYWA YQEFLNEFPE QKHLTDALAA AVRDDPVPIA
PEKRHPLKIS VVYPGQQISD YWIRNIDAFE KRLDKLNIDY QINQVFTRPN ADIKQQSLSL
MEALKSNSDY LIFTLDTTRH RKFVEHVLDS TKTKLILQNI TTPVREWETR QPFMYVGFDH
AEGSRELAVE FGKQFPKNTH YSVLYFSEGY ISDIRGNTFI HQVNQDSQFE LQSAYYTKAT
KQSGYEAAKA SLKKYPDVEF IYACSTDVAL GAVEALSELG REDVMINGWG GGSAELDAIL
KGELDITVMR MNDDTGIAMA EAIKWDLEGK PVPTVYSGDF EVVTKSDSPE RIEALRKRAF
RYSDN
//
