ID   M0AQG3_NATA1            Unreviewed;       514 AA.
AC   M0AQG3;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Carboxyl transferase {ECO:0000313|EMBL:ELZ00542.1};
GN   ORFNames=C481_12899 {ECO:0000313|EMBL:ELZ00542.1};
OS   Natrialba asiatica (strain ATCC 700177 / DSM 12278 / JCM 9576 / FERM
OS   P-10747 / NBRC 102637 / 172P1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrialba.
OX   NCBI_TaxID=29540 {ECO:0000313|EMBL:ELZ00542.1, ECO:0000313|Proteomes:UP000011554};
RN   [1] {ECO:0000313|EMBL:ELZ00542.1, ECO:0000313|Proteomes:UP000011554}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12278 {ECO:0000313|EMBL:ELZ00542.1,
RC   ECO:0000313|Proteomes:UP000011554};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ00542.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOIO01000030; ELZ00542.1; -; Genomic_DNA.
DR   RefSeq; WP_006109615.1; NZ_AOIO01000030.1.
DR   AlphaFoldDB; M0AQG3; -.
DR   STRING; 29540.C481_12899; -.
DR   PATRIC; fig|29540.5.peg.2614; -.
DR   eggNOG; arCOG02705; Archaea.
DR   OrthoDB; 30579at2157; -.
DR   Proteomes; UP000011554; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR034733; AcCoA_carboxyl_beta.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR011763; COA_CT_C.
DR   InterPro; IPR011762; COA_CT_N.
DR   PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR   PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR   Pfam; PF01039; Carboxyl_trans; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 2.
DR   PROSITE; PS50989; COA_CT_CTER; 1.
DR   PROSITE; PS50980; COA_CT_NTER; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011554};
KW   Transferase {ECO:0000313|EMBL:ELZ00542.1}.
FT   DOMAIN          1..257
FT                   /note="CoA carboxyltransferase N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50980"
FT   DOMAIN          261..507
FT                   /note="CoA carboxyltransferase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50989"
FT   REGION          249..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..272
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  56657 MW;  ED87940394B5A429 CRC64;
     MDDRIDELEA LREEARLGGG EDRIAKQHDK GKMTARERID YFLDEGTFTE FDQLRTHQTR
     QFGMDEKKIR GDGVVTGHGE VNGRTVFVFA HDFTVFGGSL GEVFAEKVCK VMDMAMEVGA
     PVIGLNDSAG ARIQEGVKSL AGYTEIFRRN QEASGVVPQI SATMGPCAGG AVYSPAITDF
     IFMVKDTSHM YITGPGVTET VTGEDVTHEE LGGAMTHADK TGVAQFACES EEQALDDIKR
     LLSYLPQNNV EDPPRVDPWD DPDRRDDRLT SIVPDSPQKP YDMTDVIDAT VDEGSFFEVG
     ENFAKNIVVG FGRLDGRSVG LVANQPRVNA GTLTVDASMK GSRFVRFCDS FNIPIVTFVD
     VPGYMPGTDQ EHRGIIRHGA KLLYAYAEAT VPLLTVITRK AYGGAYCVMA SKNLGADVNY
     AWPTAEIAVM GPKGAVNILY REELAEAENP DELREELIDE YREEFANPYT ATDKGFLDDV
     IVPTETRPRL IADLEMLETK REQNPDKKHG NIPL
//