ID   M0CFY1_9EURY            Unreviewed;       633 AA.
AC   M0CFY1;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein {ECO:0000313|EMBL:ELZ22156.1};
GN   ORFNames=C476_06997 {ECO:0000313|EMBL:ELZ22156.1};
OS   Natrinema limicola JCM 13563.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrinema.
OX   NCBI_TaxID=1230457 {ECO:0000313|EMBL:ELZ22156.1, ECO:0000313|Proteomes:UP000011615};
RN   [1] {ECO:0000313|EMBL:ELZ22156.1, ECO:0000313|Proteomes:UP000011615}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 13563 {ECO:0000313|EMBL:ELZ22156.1,
RC   ECO:0000313|Proteomes:UP000011615};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005046}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ22156.1}.
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DR   EMBL; AOIT01000029; ELZ22156.1; -; Genomic_DNA.
DR   RefSeq; WP_008011295.1; NZ_AOIT01000029.1.
DR   AlphaFoldDB; M0CFY1; -.
DR   STRING; 1230457.C476_06997; -.
DR   PATRIC; fig|1230457.4.peg.1401; -.
DR   eggNOG; arCOG00217; Archaea.
DR   OrthoDB; 31371at2157; -.
DR   UniPathway; UPA00344; -.
DR   Proteomes; UP000011615; Unassembled WGS sequence.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd00887; MoeA; 1.
DR   Gene3D; 3.40.980.10; MoaB/Mog-like domain; 1.
DR   Gene3D; 2.40.340.10; MoeA, C-terminal, domain IV; 1.
DR   Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR   Gene3D; 2.170.190.11; Molybdopterin biosynthesis moea protein, domain 3; 1.
DR   InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR   InterPro; IPR001453; MoaB/Mog_dom.
DR   InterPro; IPR008284; MoCF_biosynth_CS.
DR   InterPro; IPR038987; MoeA-like.
DR   InterPro; IPR005111; MoeA_C_domain_IV.
DR   InterPro; IPR036688; MoeA_C_domain_IV_sf.
DR   InterPro; IPR005110; MoeA_linker/N.
DR   InterPro; IPR036135; MoeA_linker/N_sf.
DR   InterPro; IPR024370; PBP_domain.
DR   NCBIfam; TIGR00177; molyb_syn; 1.
DR   PANTHER; PTHR10192:SF5; GEPHYRIN; 1.
DR   PANTHER; PTHR10192; MOLYBDOPTERIN BIOSYNTHESIS PROTEIN; 1.
DR   Pfam; PF00994; MoCF_biosynth; 1.
DR   Pfam; PF03454; MoeA_C; 1.
DR   Pfam; PF03453; MoeA_N; 1.
DR   Pfam; PF12727; PBP_like; 1.
DR   SMART; SM00852; MoCF_biosynth; 1.
DR   SUPFAM; SSF63867; MoeA C-terminal domain-like; 1.
DR   SUPFAM; SSF63882; MoeA N-terminal region -like; 1.
DR   SUPFAM; SSF53218; Molybdenum cofactor biosynthesis proteins; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   PROSITE; PS01079; MOCF_BIOSYNTHESIS_2; 1.
PE   4: Predicted;
KW   Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011615}.
FT   DOMAIN          206..345
FT                   /note="MoaB/Mog"
FT                   /evidence="ECO:0000259|SMART:SM00852"
FT   REGION          124..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   633 AA;  67096 MW;  C60ABC979A2FBF1C CRC64;
     MNRKEFRDLA TPAEAREAID SLALEAGIER VPLAEARGRV LVARLDAELD VPGFDRASLD
     GYALRARDTF GADEADPARL AVVGEVHAGE EPDITLEEGQ AVEISTGAVM PDGADAMVPV
     ERTDRVDGPS TERASGETPT DMESDGDEVL VRTAVAPGDN VMFAGADVAA GERALGPGTQ
     ITPRDIGLLS ALGIDEVPVR AKPRVGIVST GDELVRPGAD LASERGEIYD VNSYTIAAGV
     EDAGGEAVLY PHAGDEQDEM ERILREAADE CDLVLSSGST SASAVDVIYR VIEEQGELLL
     HGVSVKPGKP MLIGRLDDSA YVGLPGYPVS AMMVFRTFVA PAIREAAGLP EPASATVAGR
     LARQERYEEG RHRLMPVGLV TDGDGETLVY PVDKGSGATT SLADADGVVE VGPETDYLEQ
     GEPVTATLFS PDVRPPTLFA VGEDDPTVSR LLDGLENPRY LSVGTRPGLR RLREGVPDVA
     VVAGPLEADV ETVELGRWER EWGLVVRTGN PDEIEGLADL VDRDRRFVNR TTDSGLRSSL
     DAAIADLADD RGTTRRELTD AIDGYDLGLR AHESPARKVI AGDADAGLGL RETADRLDLG
     FVPLGEQPVR VLANPDRTAK DGVRELEAAL ADV
//