ID   M0CN68_9EURY            Unreviewed;       249 AA.
AC   M0CN68;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=HNH endonuclease {ECO:0000313|EMBL:ELZ24715.1};
GN   ORFNames=C476_03663 {ECO:0000313|EMBL:ELZ24715.1};
OS   Natrinema limicola JCM 13563.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrinema.
OX   NCBI_TaxID=1230457 {ECO:0000313|EMBL:ELZ24715.1, ECO:0000313|Proteomes:UP000011615};
RN   [1] {ECO:0000313|EMBL:ELZ24715.1, ECO:0000313|Proteomes:UP000011615}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 13563 {ECO:0000313|EMBL:ELZ24715.1,
RC   ECO:0000313|Proteomes:UP000011615};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ24715.1}.
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DR   EMBL; AOIT01000017; ELZ24715.1; -; Genomic_DNA.
DR   RefSeq; WP_008009977.1; NZ_AOIT01000017.1.
DR   AlphaFoldDB; M0CN68; -.
DR   STRING; 1230457.C476_03663; -.
DR   PATRIC; fig|1230457.4.peg.730; -.
DR   eggNOG; arCOG03898; Archaea.
DR   OrthoDB; 11472at2157; -.
DR   Proteomes; UP000011615; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00085; HNHc; 1.
DR   Gene3D; 1.10.30.50; -; 1.
DR   InterPro; IPR002711; HNH.
DR   InterPro; IPR003615; HNH_nuc.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR41286; HNH NUCLEASE YAJD-RELATED; 1.
DR   PANTHER; PTHR41286:SF1; HNH NUCLEASE YAJD-RELATED; 1.
DR   Pfam; PF01844; HNH; 1.
DR   SMART; SM00507; HNHc; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|EMBL:ELZ24715.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011615}.
FT   DOMAIN          1..29
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
SQ   SEQUENCE   249 AA;  28015 MW;  A408F2F61E54CCBF CRC64;
     MDCPTCGKSL TTERGMRQHH TKVHDESLPN RTCTGCGTEF YDPKSRLEFC DDCNPNAGEH
     NGNWKGGKET GTCDRCGATF DYYSSDKPGM YCSECVESAR GLVPGNPSEK GERVVVGCEA
     CDAELEVRPA RLEKQTRGVF CTLECYGDWL SENVVGPDHH QWEGGSIDYG QQWWQVRRQA
     LERDDYECQH CGTSAEELGR NPDVHHRRPV RSFDQPEDAH TMDNVITLCR SCHRHAEAGT
     ITLPSHDEK
//