ID M0CVB2_9EURY Unreviewed; 141 AA.
AC M0CVB2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Probable transcription termination protein NusA {ECO:0000256|HAMAP-Rule:MF_00945};
GN Name=nusA {ECO:0000256|HAMAP-Rule:MF_00945};
GN ORFNames=C476_00272 {ECO:0000313|EMBL:ELZ25839.1};
OS Natrinema limicola JCM 13563.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=1230457 {ECO:0000313|EMBL:ELZ25839.1, ECO:0000313|Proteomes:UP000011615};
RN [1] {ECO:0000313|EMBL:ELZ25839.1, ECO:0000313|Proteomes:UP000011615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13563 {ECO:0000313|EMBL:ELZ25839.1,
RC ECO:0000313|Proteomes:UP000011615};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- FUNCTION: Participates in transcription termination.
CC {ECO:0000256|HAMAP-Rule:MF_00945}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00945}.
CC -!- SIMILARITY: Belongs to the NusA family. {ECO:0000256|HAMAP-
CC Rule:MF_00945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ25839.1}.
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DR EMBL; AOIT01000010; ELZ25839.1; -; Genomic_DNA.
DR RefSeq; WP_008008688.1; NZ_AOIT01000010.1.
DR AlphaFoldDB; M0CVB2; -.
DR STRING; 1230457.C476_00272; -.
DR PATRIC; fig|1230457.4.peg.48; -.
DR eggNOG; arCOG01760; Archaea.
DR OrthoDB; 4116at2157; -.
DR Proteomes; UP000011615; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:InterPro.
DR CDD; cd22531; KH-II_NusA_arch_rpt2; 1.
DR Gene3D; 3.30.300.20; -; 2.
DR HAMAP; MF_00945_A; NusA_A; 1.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR025249; KH_dom_NusA-like.
DR InterPro; IPR009019; KH_sf_prok-type.
DR InterPro; IPR010212; NusA_arc.
DR InterPro; IPR030842; NusA_bac.
DR NCBIfam; TIGR01952; nusA_arch; 1.
DR PANTHER; PTHR22648; TRANSCRIPTION TERMINATION FACTOR NUSA; 1.
DR PANTHER; PTHR22648:SF0; TRANSCRIPTION TERMINATION_ANTITERMINATION PROTEIN NUSA; 1.
DR Pfam; PF13184; KH_5; 1.
DR SUPFAM; SSF54814; Prokaryotic type KH domain (KH-domain type II); 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00945};
KW Elongation factor {ECO:0000313|EMBL:ELZ25839.1};
KW Protein biosynthesis {ECO:0000313|EMBL:ELZ25839.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011615};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00945};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00945};
KW Transcription termination {ECO:0000256|ARBA:ARBA00022472,
KW ECO:0000256|HAMAP-Rule:MF_00945}.
FT DOMAIN 33..94
FT /note="KH"
FT /evidence="ECO:0000259|Pfam:PF13184"
SQ SEQUENCE 141 AA; 14945 MW; 57A9ECBA2BB024FD CRC64;
MGVTLADDAR QYLAAFEDVT GVAGRDCLVT DGGDRLLIVV ERGGMGEAIG PDGRTIQQFE
DRVDAQVRLV EDAADPETFV ANALAPAAVY NVTISENNDT VAYVEVAEAD HGVAIGTNGR
TIEAARTLAK RHFGIDDVQL L
//
