ID   M0F645_9EURY            Unreviewed;       522 AA.
AC   M0F645;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Circadian clock protein, KaiC {ECO:0000313|EMBL:ELZ54094.1};
GN   ORFNames=C467_12153 {ECO:0000313|EMBL:ELZ54094.1};
OS   Halorubrum hochstenium ATCC 700873.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum.
OX   NCBI_TaxID=1227481 {ECO:0000313|EMBL:ELZ54094.1, ECO:0000313|Proteomes:UP000011689};
RN   [1] {ECO:0000313|EMBL:ELZ54094.1, ECO:0000313|Proteomes:UP000011689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700873 {ECO:0000313|EMBL:ELZ54094.1,
RC   ECO:0000313|Proteomes:UP000011689};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ54094.1}.
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DR   EMBL; AOJO01000055; ELZ54094.1; -; Genomic_DNA.
DR   RefSeq; WP_008585622.1; NZ_AOJO01000055.1.
DR   AlphaFoldDB; M0F645; -.
DR   STRING; 1227481.C467_12153; -.
DR   PATRIC; fig|1227481.4.peg.2401; -.
DR   OrthoDB; 27015at2157; -.
DR   Proteomes; UP000011689; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   CDD; cd01124; KaiC-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR022420; Circ_KaiC_arc.
DR   InterPro; IPR014774; KaiC-like_dom.
DR   InterPro; IPR010624; KaiC_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR03880; KaiC_arch_3; 1.
DR   PANTHER; PTHR43637:SF1; UPF0273 PROTEIN MJ1359; 1.
DR   PANTHER; PTHR43637; UPF0273 PROTEIN TM_0370; 1.
DR   Pfam; PF06745; ATPase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51146; KAIC; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011689}.
FT   DOMAIN          293..522
FT                   /note="KaiC"
FT                   /evidence="ECO:0000259|PROSITE:PS51146"
FT   REGION          1..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..52
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   522 AA;  53169 MW;  28D10121E66F7386 CRC64;
     MSEEDDWFER ALRETDEESD EQPVEGEATD DGDGGEPEPE ASDEAAESDD ADGVPDDPAR
     AIGIGTDDGS GEDDAFGGGE AGGEPFGGGD EAGGDPFGGS EGGPAADDSG NDGVPAGAFG
     DVDTDADGGE FGSFGGSDSF GDDDPFGGGG GVDTDADGGE FGSFGGSDSF GDDDPFGGGG
     GDAGSDAESG PSGETGGSGG TDPFGDDDPF GGSRSGMSGG GSSGAGGGGG ASGAESPGGS
     AGDAGSDPFG GYRGSAARDG DDFGFDDLDG GEGGPGDATD FDVDPDEFES GIDRTDIGIE
     GLDDMILGGV PSRSLLSVIG GAGTGKTTFA LQFLNHALEA GNKGIYITLE QTRESIYDTA
     EEKGWPFREH ADADRLAVVA IDPIEMANSL SSIRNDLVRL IAEFDADRLV LDSVSLLEMM
     YDHPAKRRSE VFGFTRSLKE AGVTTLLTSE ASEETPYASR HGIVEYLTDA VFVLQYVRGS
     DFRETRLAVE IQKIRDANHS RETKPYDITD TGISVYDQAN IF
//