ID M0FPJ0_9EURY Unreviewed; 326 AA.
AC M0FPJ0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Formyl transferase {ECO:0000313|EMBL:ELZ61203.1};
GN ORFNames=C467_01683 {ECO:0000313|EMBL:ELZ61203.1};
OS Halorubrum hochstenium ATCC 700873.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1227481 {ECO:0000313|EMBL:ELZ61203.1, ECO:0000313|Proteomes:UP000011689};
RN [1] {ECO:0000313|EMBL:ELZ61203.1, ECO:0000313|Proteomes:UP000011689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700873 {ECO:0000313|EMBL:ELZ61203.1,
RC ECO:0000313|Proteomes:UP000011689};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ61203.1}.
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DR EMBL; AOJO01000007; ELZ61203.1; -; Genomic_DNA.
DR RefSeq; WP_008581206.1; NZ_AOJO01000007.1.
DR AlphaFoldDB; M0FPJ0; -.
DR STRING; 1227481.C467_01683; -.
DR GeneID; 72714702; -.
DR PATRIC; fig|1227481.4.peg.313; -.
DR OrthoDB; 27277at2157; -.
DR Proteomes; UP000011689; Unassembled WGS sequence.
DR GO; GO:0008864; F:formyltetrahydrofolate deformylase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.170; Formyl transferase, N-terminal domain; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR036477; Formyl_transf_N_sf.
DR InterPro; IPR004810; PurU.
DR PANTHER; PTHR42706; FORMYLTETRAHYDROFOLATE DEFORMYLASE; 1.
DR PANTHER; PTHR42706:SF1; FORMYLTETRAHYDROFOLATE DEFORMYLASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF13740; ACT_6; 1.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR PIRSF; PIRSF036480; FormyFH4_hydr; 1.
DR PRINTS; PR01575; FFH4HYDRLASE.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53328; Formyltransferase; 1.
DR PROSITE; PS51671; ACT; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563};
KW Reference proteome {ECO:0000313|Proteomes:UP000011689};
KW Transferase {ECO:0000313|EMBL:ELZ61203.1}.
FT DOMAIN 7..81
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT REGION 301..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 326 AA; 35847 MW; F1666132C6DFEA8A CRC64;
MTRELTEITV VGGDKTGLIA RVTSLLFERG INIEDLDQAV REGVFRMTTR VDTAEMETSR
GELRRALAEL GRELDVDIQV RFPSDRDARR IALLVTKETH APEALLEAEA NGDLADDGEE
AEIPVVIGNR GDLRSLAERY DKPFYDVGDG SGNTDEERLL DLLAEYDVDL IALARYMRIL
SPEVVFRYEG RIINVHPSLL PAFPGAEAYR QAKDAGVRIA GVTAHYVTTD LDQGPVIAQR
AFDVPPNADV DEIKRRGQPL EADVLLDAVR LHLADAIAVH RGTVHVREEV DVDAQLGLSE
AAVEANPDEP VDGEPLTRSR PSPSDD
//
