ID M0LRQ8_9EURY Unreviewed; 444 AA.
AC M0LRQ8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Potassium transporter peripheral membrane component {ECO:0000313|EMBL:EMA36161.1};
GN Name=trkA {ECO:0000313|EMBL:EMA36161.1};
GN ORFNames=C447_15351 {ECO:0000313|EMBL:EMA36161.1};
OS Halococcus hamelinensis 100A6.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=1132509 {ECO:0000313|EMBL:EMA36161.1, ECO:0000313|Proteomes:UP000011566};
RN [1] {ECO:0000313|EMBL:EMA36161.1, ECO:0000313|Proteomes:UP000011566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=100A6 {ECO:0000313|EMBL:EMA36161.1,
RC ECO:0000313|Proteomes:UP000011566};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- FUNCTION: Part of a potassium transport system.
CC {ECO:0000256|ARBA:ARBA00003660}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA36161.1}.
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DR EMBL; AOMB01000042; EMA36161.1; -; Genomic_DNA.
DR RefSeq; WP_007695422.1; NZ_AOMB01000042.1.
DR AlphaFoldDB; M0LRQ8; -.
DR PATRIC; fig|1132509.6.peg.3565; -.
DR eggNOG; arCOG01959; Archaea.
DR OrthoDB; 27588at2157; -.
DR Proteomes; UP000011566; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000011566}.
FT DOMAIN 2..127
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 139..220
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 228..351
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 363..444
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 444 AA; 47344 MW; F9B642015A414DC6 CRC64;
MRVIIVGAGQ VGSTIAANLD ANHEVVVIDI DDDRVENLMY SYDVLAIEGN GAALPTLREA
DVERADMVIA STDDDETNIV ACAAAKTVSD AFTVARVRGT THLDTWQEAG GAFGVDFMVS
TDLLAAETVA RVIGLPAARD VDTFADGSVL MAEFSLPPES PLVDRTVAEA DRFDEVTIAA
VIREHEVIIP KGETTFAAGD DLVAIGSPEG IRAFAGELTP DQQGEGKDVV VVGGSEVALQ
TAVILEDRGL HPRLIERDPE RARELAERLP HTTVLSSDAT DREFLTREHI GDADVVVAAL
DSDEKTLLAS LLADRIGVDR TIALVETAQY ASLFEAVGVD AAINPRDATA EEIIRFSREG
STENVAIIDD DRAEVLEIEV DTESVLAGRP IRESAADLPE SVTIGAITRD GRYIIPRGDT
EVEVGDHVVL FAETRSIDAV AARV
//
