ID   M0LXE9_9EURY            Unreviewed;       757 AA.
AC   M0LXE9;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=CARDB domain-containing protein {ECO:0000313|EMBL:EMA37853.1};
GN   ORFNames=C446_10520 {ECO:0000313|EMBL:EMA37853.1};
OS   Halobiforma nitratireducens JCM 10879.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Halobiforma.
OX   NCBI_TaxID=1227454 {ECO:0000313|EMBL:EMA37853.1, ECO:0000313|Proteomes:UP000011607};
RN   [1] {ECO:0000313|EMBL:EMA37853.1, ECO:0000313|Proteomes:UP000011607}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10879 {ECO:0000313|EMBL:EMA37853.1,
RC   ECO:0000313|Proteomes:UP000011607};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA37853.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOMA01000102; EMA37853.1; -; Genomic_DNA.
DR   RefSeq; WP_006673019.1; NZ_AOMA01000102.1.
DR   AlphaFoldDB; M0LXE9; -.
DR   PATRIC; fig|1227454.3.peg.2139; -.
DR   eggNOG; arCOG00702; Archaea.
DR   OrthoDB; 206329at2157; -.
DR   Proteomes; UP000011607; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   Pfam; PF18911; PKD_4; 1.
DR   SUPFAM; SSF49478; Cna protein B-type domain; 1.
DR   SUPFAM; SSF49299; PKD domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011607};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        720..741
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          34..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..64
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..115
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   757 AA;  79539 MW;  03CCB3484A9D59E4 CRC64;
     MSGPLTGLAA KWALVVGLLA LLVAVTAVPA IAGAEPAAVT GDDEQRTESG QLTTGGVDAN
     EDNDGNNGND GDEEDDGDGG DDGEDGNDDD DESDEDDGDD GDNGDDEDDE NETAVEPTAV
     VDAPDSIGVG TTVTLDASDS EPEDEIESYN WTIHEEDGTY LENTSVPTLE YTFDDPGDKD
     VFLEVETDEK RAATSTVVDV EKPTVTGSVV HHDGDASASD KVALYDGDEA ITTAETADDG
     SFTLPIEEPG TYGLIYRNDD LLSGESDFDP DGRVDLYAIE TITVDDGSAD IGTVTLPEPN
     DLEIVVVGSE SDLPVENATV TYTHEHDGVS ASTVVSTGEE GYAPAEEETP IGVVGDIDIE
     IETPDGFIEE SVSESMTVNR DTQKRIELQE RINASLAVEQ EPVPVGENVT VTLEENRGTA
     QTISWTVGGE RTTETQNRSI DIVVTGPKID NETVDIAATV TGVNGKSDDP ETSVPVNLPE
     LQLNAPERTN AYESFTATAS YDTKSGEIGV ERYDWQLYDE NGSVVDSKRP AGSSVAFAVD
     SVGNYTIDLS VRDESDYTVS ANTTVEVDTV PSWVEFGASY VEIEDVSAPS SVETGETVSI
     TVTATNVGEE PDVSEISVAN ETALLEQRTV ELGDGETDTV TLEYTAPDRP GNDTLSISTG
     DDRASHSYTV VANSSSNATA NGDGENGTAD GPQQLDLLPT PAVGAEVSGA SMSSDRLGTV
     LLGTATTTIL GGFGLLGYVV YTRPRESGAE WLLPGRE
//