ID M0LYF4_9EURY Unreviewed; 583 AA.
AC M0LYF4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Ammonium transporter {ECO:0000313|EMBL:EMA38208.1};
GN ORFNames=C446_10175 {ECO:0000313|EMBL:EMA38208.1};
OS Halobiforma nitratireducens JCM 10879.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Halobiforma.
OX NCBI_TaxID=1227454 {ECO:0000313|EMBL:EMA38208.1, ECO:0000313|Proteomes:UP000011607};
RN [1] {ECO:0000313|EMBL:EMA38208.1, ECO:0000313|Proteomes:UP000011607}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10879 {ECO:0000313|EMBL:EMA38208.1,
RC ECO:0000313|Proteomes:UP000011607};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the P(II) protein family.
CC {ECO:0000256|RuleBase:RU003936}.
CC -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC family. {ECO:0000256|ARBA:ARBA00005887}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA38208.1}.
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DR EMBL; AOMA01000099; EMA38208.1; -; Genomic_DNA.
DR RefSeq; WP_006672950.1; NZ_AOMA01000099.1.
DR AlphaFoldDB; M0LYF4; -.
DR STRING; 1227454.C446_10175; -.
DR PATRIC; fig|1227454.3.peg.2067; -.
DR eggNOG; arCOG02305; Archaea.
DR eggNOG; arCOG04397; Archaea.
DR OrthoDB; 10960at2157; -.
DR Proteomes; UP000011607; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR GO; GO:0006808; P:regulation of nitrogen utilization; IEA:InterPro.
DR Gene3D; 3.30.70.120; -; 1.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR018047; Ammonium_transpt_CS.
DR InterPro; IPR002187; N-reg_PII.
DR InterPro; IPR011322; N-reg_PII-like_a/b.
DR InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR InterPro; IPR017918; N-reg_PII_CS.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR PANTHER; PTHR11730:SF6; AMMONIUM TRANSPORTER; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR Pfam; PF00543; P-II; 1.
DR PRINTS; PR00340; PIIGLNB.
DR SMART; SM00938; P-II; 1.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
DR SUPFAM; SSF54913; GlnB-like; 1.
DR PROSITE; PS01219; AMMONIUM_TRANSP; 1.
DR PROSITE; PS00638; PII_GLNB_CTER; 1.
DR PROSITE; PS51343; PII_GLNB_DOM; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|PIRSR:PIRSR602187-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000011607};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..434
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
FT REGION 437..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 522
FT /note="O-UMP-tyrosine"
FT /evidence="ECO:0000256|PIRSR:PIRSR602187-50"
SQ SEQUENCE 583 AA; 60157 MW; 061E8966746BDE9D CRC64;
MIEPPLLEVS SSDLESLATG MNLMWALTVT FLIFFMHAGF AMLEAGQVRS KNVANQLTKN
MLTWAVGIGV FFVIGMGISN NVGAALAGGE STPLTMFGEG SFDWVMWLFS AVFAMTAATI
VSGAVAGRAK LRAYVAYTFL LAAVIYPVVA GLVWYAPGAD APLLDAFGFA DFAGGMVVHG
VGGVAGLTAA WILGARIDKY ADDGSVNVLP GHSLTFAVLG TLILCFGWFG FNVGTAATVV
DPGSFELADF DYVGSVAMVT ALGMGLGAVG ASAVSIVTIG KVDTLYVANG MLAGLVGVTG
PTDLITPMGA IAIGFLAGAQ LPLVFRFVEQ YLKIDDVCAV FPVHGSAGML GLILYPLWSI
EGTAIGGGLV AGGLLSIEAG AFVPQIVGVA VLTVWTVVTT AAIWGAFKAA GQARVTPEHE
RDGLDLAEHG VDTYPEFGKP DVATDGGTAG HGSDGDSSVL RADGGEPNDG EIKMVTAIVR
PDRLSAVKTE LAQIGAPSLT VTNVSGRGSQ PAKKGQWRGE EYTVDLHQKA KIECVVADVP
AADVITAVRE AANTGEPGDG KIFVQTIEDA CQIRTGKRGR EAV
//
