ID   M0M145_9EURY            Unreviewed;       315 AA.
AC   M0M145;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Lactoylglutathione lyase {ECO:0000313|EMBL:EMA38349.1};
GN   ORFNames=C447_09332 {ECO:0000313|EMBL:EMA38349.1};
OS   Halococcus hamelinensis 100A6.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halococcaceae; Halococcus.
OX   NCBI_TaxID=1132509 {ECO:0000313|EMBL:EMA38349.1, ECO:0000313|Proteomes:UP000011566};
RN   [1] {ECO:0000313|EMBL:EMA38349.1, ECO:0000313|Proteomes:UP000011566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=100A6 {ECO:0000313|EMBL:EMA38349.1,
RC   ECO:0000313|Proteomes:UP000011566};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA38349.1}.
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DR   EMBL; AOMB01000030; EMA38349.1; -; Genomic_DNA.
DR   RefSeq; WP_007693211.1; NZ_AOMB01000030.1.
DR   AlphaFoldDB; M0M145; -.
DR   PATRIC; fig|1132509.6.peg.2107; -.
DR   eggNOG; arCOG03101; Archaea.
DR   OrthoDB; 9710at2157; -.
DR   Proteomes; UP000011566; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 2.
DR   InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR   InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR   InterPro; IPR037523; VOC.
DR   PANTHER; PTHR36110; RING-CLEAVING DIOXYGENASE MHQE-RELATED; 1.
DR   PANTHER; PTHR36110:SF2; RING-CLEAVING DIOXYGENASE MHQE-RELATED; 1.
DR   Pfam; PF00903; Glyoxalase; 1.
DR   SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR   PROSITE; PS51819; VOC; 2.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:EMA38349.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011566}.
FT   DOMAIN          6..131
FT                   /note="VOC"
FT                   /evidence="ECO:0000259|PROSITE:PS51819"
FT   DOMAIN          151..275
FT                   /note="VOC"
FT                   /evidence="ECO:0000259|PROSITE:PS51819"
SQ   SEQUENCE   315 AA;  35080 MW;  2390172BCEBD5189 CRC64;
     MGEISRLHHV TAFASDPQRN LDFFTEVIGL RFIKRTVRFD IPEEIYHLYY GDEAGTAGSI
     VTYFPVTDMN EGLVGKGQIS AAGLVIPEGS VEYWTDRFEE HDVEHTVEER FGETAIGFTD
     PDGTPFELVT GESDIEPWDG GPVPAEHGVR GLHGVTIHSN DPAGTFRALE TMDWSRVGRA
     DYPQAGDHVR YEAPGDRRGA NVVDVLVRPN APQGVQGTGT FLHVAFDTGE KWEQKEWSER
     FREAGLITTS RKDRDYFWSM YFTEPGGTTF EFATEGPGVT LDESVEALGS ELKVPDWLDV
     DVSEIDEQLP DLTTD
//