ID M0M1C9_9EURY Unreviewed; 558 AA.
AC M0M1C9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Acyl-CoA synthetase {ECO:0000313|EMBL:EMA39228.1};
GN ORFNames=C447_06918 {ECO:0000313|EMBL:EMA39228.1};
OS Halococcus hamelinensis 100A6.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=1132509 {ECO:0000313|EMBL:EMA39228.1, ECO:0000313|Proteomes:UP000011566};
RN [1] {ECO:0000313|EMBL:EMA39228.1, ECO:0000313|Proteomes:UP000011566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=100A6 {ECO:0000313|EMBL:EMA39228.1,
RC ECO:0000313|Proteomes:UP000011566};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA39228.1}.
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DR EMBL; AOMB01000020; EMA39228.1; -; Genomic_DNA.
DR RefSeq; WP_007692222.1; NZ_AOMB01000020.1.
DR AlphaFoldDB; M0M1C9; -.
DR PATRIC; fig|1132509.6.peg.1568; -.
DR eggNOG; arCOG04201; Archaea.
DR OrthoDB; 193284at2157; -.
DR Proteomes; UP000011566; Unassembled WGS sequence.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000011566}.
FT DOMAIN 48..408
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 462..540
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 558 AA; 61547 MW; FFF1B6F5FFB99992 CRC64;
MATHNLPDYE AARESFSWTD IYDEADWDAP DELNIAHEVC DRHADGSGRV ALEYAGVEGE
RETLTFDDLA ERSNRFANLL ENQDVERGDR VFTYLPRIPA HYVALVGTLK RGAVFGGVNE
RFGPEGIAYR LVDCDATAVV TTSANRETVE RALADVPTVE TVVTIDRGDG IEEGDVDYER
AMADAGTDYD LVRTGSEDDA LLYYTSGTTG LAKGVLHRHR WVAGVAATQR YAVDLRDDDL
YWSTADLGWL TGPINTLGAW FWGTSQFAYE GEFSPQEWAS LLSEYPITVL FSVPTAYRML
RANEDVLDAD LDLRHALSIG EPLSAGVVEW AEDALGVTVL DTYGQTETGN MVINNYPTME
LRPGSMGKPL PGIESAIVDP ETGEVLPPGE TGEIAHRGDF PCFFAEYWNN PGKTAACFVE
GSDGRWYRSG DLAHRDEDGY FWFEGRADDV ILSSGYRIGP FEVESSLGEH PAVAEAAVVP
KPHPERGNIV KAYVVLAGGY DPSDDLAEGI RTHVREELSA HEYPREVEFV DDLPKTVTGK
IRRTELRDRT AETDSTAD
//
