ID   M0M4X8_9EURY            Unreviewed;       725 AA.
AC   M0M4X8;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:EMA40867.1};
GN   ORFNames=C446_06810 {ECO:0000313|EMBL:EMA40867.1};
OS   Halobiforma nitratireducens JCM 10879.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Halobiforma.
OX   NCBI_TaxID=1227454 {ECO:0000313|EMBL:EMA40867.1, ECO:0000313|Proteomes:UP000011607};
RN   [1] {ECO:0000313|EMBL:EMA40867.1, ECO:0000313|Proteomes:UP000011607}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10879 {ECO:0000313|EMBL:EMA40867.1,
RC   ECO:0000313|Proteomes:UP000011607};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA40867.1}.
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DR   EMBL; AOMA01000070; EMA40867.1; -; Genomic_DNA.
DR   RefSeq; WP_006672303.1; NZ_AOMA01000070.1.
DR   AlphaFoldDB; M0M4X8; -.
DR   STRING; 1227454.C446_06810; -.
DR   PATRIC; fig|1227454.3.peg.1368; -.
DR   eggNOG; arCOG00770; Archaea.
DR   OrthoDB; 27512at2157; -.
DR   Proteomes; UP000011607; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.275.40; -; 1.
DR   Gene3D; 1.10.30.20; Bacterial XPD DNA helicase, FeS cluster domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006555; ATP-dep_Helicase_C.
DR   InterPro; IPR045028; DinG/Rad3-like.
DR   InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR   InterPro; IPR006554; Helicase-like_DEXD_c2.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR   InterPro; IPR042493; XPD_DNA_FeS.
DR   PANTHER; PTHR11472:SF65; DNA HELICASE REPD; 1.
DR   PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR   Pfam; PF06733; DEAD_2; 1.
DR   Pfam; PF13307; Helicase_C_2; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00488; DEXDc2; 1.
DR   SMART; SM00491; HELICc2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EMA40867.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011607}.
FT   DOMAIN          6..310
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51193"
FT   COILED          116..175
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   725 AA;  81713 MW;  47789DB01A2153B9 CRC64;
     MSETAGYMRF FPYEQPYENQ REAMDRIHNA LTRGQDVLFE GACGTGKTLS SLVPALEVAR
     ENDKTVVITT DVHQQMRQFV AEARAITSEE DVRAIVFKGK GSMCHIDVGY EECQTLRDNT
     RAIVDAEEER DQLERRQREL LAESQDGDGS AADARSAVMD ELESIEDRLE DLEEQNVCDY
     YRNNLTENTD DFFAWLFEDV RRPEEIYEYA ESQELCGYEL LKEGIEGVDL VVCNYHHLLD
     STIREQFFRW LGRDPEDVIA VFDEAHNVED AAREHATRTC SERTFESALD ELEESDDPRA
     QDAGNVLSAF HRALVETYED SFGFGEREAI GENWADVPIA NEDRRDDLTL EFLQRYSGRG
     IEDDLEAAMT LGQELDEEYE EAYREGETAT RTECQTLQAA GFVSAWMNEG GNDGLYPVVS
     VTRDAGTDEV YGRAEIYSCL PRQVTGRLFE EVYATVLMSA TLQPFDVTED VLGLESPVTM
     AYGLQFPEEN RRTYAVETPP LFSSDRDDPA VQEAVTDAIY DAARMTSGNT LAFFPNYSEA
     GRYADRLEGR LGGEGTVYTD EPGVAVEDIR REFVADDGAV LCTSLWGTLA EGVSFDGEDA
     RTVLVVGVPY PHLDDRAEAV QEAYDAAFDG TETGWRYAVE IPTVRKTRQA LGRVIRSPED
     VGVRALLDQR YSKRAKSDIG RYSVNSTFPY EEREELIDIE PEKLKFAMLN FFGGHDAYDG
     EPPAP
//