ID M0M807_9EURY Unreviewed; 775 AA.
AC M0M807;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=DEAD/DEAH box helicase domain-containing protein {ECO:0000313|EMBL:EMA40500.1};
GN ORFNames=C447_04352 {ECO:0000313|EMBL:EMA40500.1};
OS Halococcus hamelinensis 100A6.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=1132509 {ECO:0000313|EMBL:EMA40500.1, ECO:0000313|Proteomes:UP000011566};
RN [1] {ECO:0000313|EMBL:EMA40500.1, ECO:0000313|Proteomes:UP000011566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=100A6 {ECO:0000313|EMBL:EMA40500.1,
RC ECO:0000313|Proteomes:UP000011566};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA40500.1}.
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DR EMBL; AOMB01000011; EMA40500.1; -; Genomic_DNA.
DR RefSeq; WP_007691277.1; NZ_AOMB01000011.1.
DR AlphaFoldDB; M0M807; -.
DR PATRIC; fig|1132509.6.peg.1006; -.
DR eggNOG; arCOG00553; Archaea.
DR OrthoDB; 371946at2157; -.
DR Proteomes; UP000011566; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EMA40500.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011566}.
FT DOMAIN 28..197
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 232..424
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 775 AA; 84842 MW; 449E2C6F76278E6D CRC64;
MSVAETVPEF ADAFAFEEFN RMQREALPAI LEREENVVAS APTASGKTAL AELAICKCLR
TGGTALFIAP LRALTNEKES EWERFESMGY SVYVVTGERD LVPHRAERAD ILVMTPEKVD
SATRKHDSPR YGFITDVSCC VIDEVHLLDS EKRGSVLEVT ISRLRRLCDP RVVALSATMP
NVGDIADWLD APPETTFDFG DEYRPVDLES GVRTYTHGEN AFADKYRRLY RALDLAEDHI
REEGQALVFV ASRQDTVRAA EKARDELASR DVPMGARGDY DFHTESQVLE NQTLRNSVLD
GVAFHHAGLS KSDKDHVEEW FREGKVQLLF STSTLAWGVN LPARCVVIRD TKYHDPLEGE
VDMSPLDVLQ MLGRAGRPGY DDAGYAYVVC DAADADKYRK LLRDGKEIDS HLAADLDTHL
NAEIAMGTIR DVGDVMDWLE TTFGFVRAKN NHVTDAVETL REAVRETLSE LRDRGFIETD
DLDVAATPLG TLTSSYYLRL PTARRFFDLA GTGPSVRAIL ETVARSTEFD SVNARRAERD
AIAGVLGSGD DLDSGPRKVL AILESSTRGS TPAELRSDAW VIRQNALRLL AALGAFLDRF
GSAWEANRAC RVAARIENGV GEDAAALTAI DGVGPGRASK LASSGIETPA DVVSAGVDEL
VEVGLSEGVA ERVVERARAL PALDIDWGAF PERIARGEND LCEVTVENRG EGARAGLRVT
VNDTQMTETA SFLGTETLPA PVFGGDPDTL TFAVEVVFPD LPLPPVTETR TVWVD
//
