ID M0MAC7_9EURY Unreviewed; 399 AA.
AC M0MAC7;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=IclR-like transcriptional regulator {ECO:0000313|EMBL:EMA42701.1};
GN ORFNames=C449_16203 {ECO:0000313|EMBL:EMA42701.1};
OS Halococcus saccharolyticus DSM 5350.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=1227455 {ECO:0000313|EMBL:EMA42701.1, ECO:0000313|Proteomes:UP000011669};
RN [1] {ECO:0000313|EMBL:EMA42701.1, ECO:0000313|Proteomes:UP000011669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5350 {ECO:0000313|EMBL:EMA42701.1,
RC ECO:0000313|Proteomes:UP000011669};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA42701.1}.
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DR EMBL; AOMD01000033; EMA42701.1; -; Genomic_DNA.
DR RefSeq; WP_006079098.1; NZ_AOMD01000033.1.
DR AlphaFoldDB; M0MAC7; -.
DR STRING; 1227455.C449_16203; -.
DR PATRIC; fig|1227455.4.peg.3299; -.
DR InParanoid; M0MAC7; -.
DR OrthoDB; 284722at2157; -.
DR Proteomes; UP000011669; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR028974; TSP_type-3_rpt.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR37467; EXPORTED CALCIUM-BINDING GLYCOPROTEIN-RELATED; 1.
DR PANTHER; PTHR37467:SF1; EXPORTED CALCIUM-BINDING GLYCOPROTEIN-RELATED; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF18884; TSP3_bac; 3.
DR SUPFAM; SSF103647; TSP type-3 repeat; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011669};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 251..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 327..366
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|Pfam:PF09339"
FT REGION 174..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 399 AA; 42399 MW; 86E8325A31052429 CRC64;
MSDRARVMAG VLCLVVLVGT GLPVGGQSVS AGGIGDVSVT GSGVVTGSVA GNDSNYVWQD
EPIDVSATFQ DSPEFTNYRV CLGYERADAP PQELVDCDRK PLSPGTNGTS EFTNVTWPSN
VTGEQELVVE LQGLSNQYNA TLLDRKTVPV TVITRTGDAD ADGLSNQQEV EQGYNLSNPD
MDSDGLNDGP EVNRYGTNPQ DPDTDGDGVR DGEELEVGSD PSAADTDGDW LSDGTELNLL
RTNPTSGLTP VWLVGLVVLV GGTIVFGGTR FRRWWRDRDG SGATETGGPS DPDDGDGVAA
DESEAKPEPS PEPAPEPLTD EDRVQTLLRE HGGRMKQTRI VEETDWSKAK VSRLLSSMND
EGTVEKLSIG RENIVSLDGH GPEAARSPHE EPAEENASD
//
