ID M0MFX4_HALMO Unreviewed; 711 AA.
AC M0MFX4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Nuclease {ECO:0000313|EMBL:EMA44606.1};
GN ORFNames=C448_08139 {ECO:0000313|EMBL:EMA44606.1};
OS Halococcus morrhuae DSM 1307.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=931277 {ECO:0000313|EMBL:EMA44606.1, ECO:0000313|Proteomes:UP000011568};
RN [1] {ECO:0000313|EMBL:EMA44606.1, ECO:0000313|Proteomes:UP000011568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1307 {ECO:0000313|EMBL:EMA44606.1,
RC ECO:0000313|Proteomes:UP000011568};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA44606.1}.
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DR EMBL; AOMC01000106; EMA44606.1; -; Genomic_DNA.
DR AlphaFoldDB; M0MFX4; -.
DR STRING; 931277.C448_08139; -.
DR PATRIC; fig|931277.6.peg.1592; -.
DR eggNOG; arCOG01310; Archaea.
DR eggNOG; arCOG01312; Archaea.
DR eggNOG; arCOG03192; Archaea.
DR Proteomes; UP000011568; Unassembled WGS sequence.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 2.40.50.90; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR InterPro; IPR002071; Thermonucl_AS.
DR Pfam; PF00565; SNase; 1.
DR SMART; SM00318; SNc; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 2.
DR SUPFAM; SSF50199; Staphylococcal nuclease; 1.
DR PROSITE; PS01123; TNASE_1; 1.
DR PROSITE; PS50830; TNASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011568}.
FT DOMAIN 240..394
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT REGION 496..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..520
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 711 AA; 75438 MW; 56C0E6E3ADB89618 CRC64;
MFDSTASLLD ATGAPLTDDS LVAVRAEPTA YNSDEDGNGD AVSYPDETPI PLVASDDGAV
GIGAPIGQDD SDFNYGNEEF LLNILDAEAG GPAVVFDEGH GQFYDTDSFS AFIGYAENNG
YEITATTDIT GSLAETDAAI ITSPADAFST AERDALAGFV ESGGALLLFD QSDFSNHDAT
SNLNAIAEAI GVKFRFNDDQ VYDPENNLYA DFVPVTSAFN TAFDYFADRD GLGLELDPQK
TYTVEVVKVT DGDTVDVRFE GGQEVAIRVL GIDTPETGSA TDTERAEEWE GIGSYDYLEK
AGNAATEFAS TELSPGDSVD LSFDTNEPVR DEFGRLLGYL TYDADGSGTR ETLYNRHVIE
AGHARVYDSG LARHDDFLAT ELDAREDGRN VWDESDPGDS EPIRNDPVEE LFVPRAAIVE
STRGDLDERV PVRAEDTAAT PNASLIAVDD DAGVALVGSP LVDEAYETAE GYPVDTSGYG
NYVFLTQLLS RTAAIGAEGP PSHAGPPDHA GPPDHAGPPD HAGPPDNHSR GGPPPHAGPP
DHAGPPERDE PEEYGDAPIL IDGGHGQFEA SYALSAEDAA YYQRYLEGVG IAFEGINEPG
SDVGTELLDE ARALLITAPS EAYTDAELAA VRTFRENGGA VVLLGGAVPE TARANLNAIA
DALGSDLRLG EAVTDETNNV NDDPSILVTS NFTERFMLFD TYTGETEYEN E
//
