ID M0MIN0_HALMO Unreviewed; 422 AA.
AC M0MIN0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Macrolide-efflux protein / Permease {ECO:0000313|EMBL:EMA44310.1};
GN ORFNames=C448_08554 {ECO:0000313|EMBL:EMA44310.1};
OS Halococcus morrhuae DSM 1307.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=931277 {ECO:0000313|EMBL:EMA44310.1, ECO:0000313|Proteomes:UP000011568};
RN [1] {ECO:0000313|EMBL:EMA44310.1, ECO:0000313|Proteomes:UP000011568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1307 {ECO:0000313|EMBL:EMA44310.1,
RC ECO:0000313|Proteomes:UP000011568};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA44310.1}.
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DR EMBL; AOMC01000109; EMA44310.1; -; Genomic_DNA.
DR AlphaFoldDB; M0MIN0; -.
DR PATRIC; fig|931277.6.peg.1674; -.
DR eggNOG; arCOG00135; Archaea.
DR Proteomes; UP000011568; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR23513:SF6; MULTIDRUG EFFLUX PUMP TAP; 1.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011568};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 422 AA; 44125 MW; FDBA24876D1DBAD9 CRC64;
MWRNADFRRF FAGQFVTNAG DSLYTVAMLW LAFELSGSTL VTGALNAILL LPWLLQVFAG
PIVDRLRLER VLVGSQIIQG IVVLILPLVA ALNYLHVGVL FAVAPILMLA SLLMAPMETA
LLPRIVDDER LPGANAALST VTLGLDMVFD ALGGGFVALF GATTLFLADS ATFAGAALLF
AGIRLGVATQ TDERTKPRAE TVVPTVRSVL RSYVSDLRDG VRMLRGTVFV ELILTTAVAN
FTTGVTLAIL PAFGDGLGGP AVYGLLLGAL GIGRLVGSLV GPWFEGVPYG RVLLVHGLAA
CCWLAAVLVS SPALTVVLFG LAWVPVGISG VLSSTLNQRV FPADLLGRIS ATKGTASGAT
LPLGSLIGGA IAEMLGTTTT MALAASGFGF TAVYVLFRPR LRRLPAIGTA TPDDFDVEAE
VE
//
