ID M0MUA2_HALMO Unreviewed; 244 AA.
AC M0MUA2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EMA48903.1};
GN ORFNames=C448_02206 {ECO:0000313|EMBL:EMA48903.1};
OS Halococcus morrhuae DSM 1307.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=931277 {ECO:0000313|EMBL:EMA48903.1, ECO:0000313|Proteomes:UP000011568};
RN [1] {ECO:0000313|EMBL:EMA48903.1, ECO:0000313|Proteomes:UP000011568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1307 {ECO:0000313|EMBL:EMA48903.1,
RC ECO:0000313|Proteomes:UP000011568};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA48903.1}.
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DR EMBL; AOMC01000043; EMA48903.1; -; Genomic_DNA.
DR RefSeq; WP_004051571.1; NZ_AOMC01000043.1.
DR AlphaFoldDB; M0MUA2; -.
DR STRING; 931277.C448_02206; -.
DR PATRIC; fig|931277.6.peg.426; -.
DR eggNOG; arCOG00245; Archaea.
DR OrthoDB; 24743at2157; -.
DR Proteomes; UP000011568; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000011568}.
FT DOMAIN 1..244
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 244 AA; 25991 MW; 550DDAA629534D9C CRC64;
MTLLVVGAGT MGEWFARTLA EATTVTLTDT DPERAAAVAD RLDARSVALD TDERFDTVCF
AVPMPAVEAA IAEHAPTAER AVIDVTGSMA EPIEAMRTHA PDRERLSLHP LFAPENAPGR
IATVADAAGP ATDEVRAALA AENELFETTP DEHDRAMETV QAGAHAAVLA YALAAEDVRE
EFHTPISGPL DDLASQVLSG SPRVYAEIQE RFDGAEAVAE AAERIATVDG TGVEELYREA
REQR
//
