ID   M0NNA9_9EURY            Unreviewed;       665 AA.
AC   M0NNA9;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein {ECO:0000313|EMBL:EMA59286.1};
GN   ORFNames=C469_11676 {ECO:0000313|EMBL:EMA59286.1};
OS   Halorubrum lipolyticum DSM 21995.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum.
OX   NCBI_TaxID=1227482 {ECO:0000313|EMBL:EMA59286.1, ECO:0000313|Proteomes:UP000011650};
RN   [1] {ECO:0000313|EMBL:EMA59286.1, ECO:0000313|Proteomes:UP000011650}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21995 {ECO:0000313|EMBL:EMA59286.1,
RC   ECO:0000313|Proteomes:UP000011650};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005046}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA59286.1}.
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DR   EMBL; AOJG01000030; EMA59286.1; -; Genomic_DNA.
DR   RefSeq; WP_008006775.1; NZ_AOJG01000030.1.
DR   AlphaFoldDB; M0NNA9; -.
DR   STRING; 1227482.C469_11676; -.
DR   PATRIC; fig|1227482.3.peg.2357; -.
DR   OrthoDB; 31371at2157; -.
DR   UniPathway; UPA00344; -.
DR   Proteomes; UP000011650; Unassembled WGS sequence.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd00887; MoeA; 1.
DR   Gene3D; 3.40.980.10; MoaB/Mog-like domain; 1.
DR   Gene3D; 2.40.340.10; MoeA, C-terminal, domain IV; 1.
DR   Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR   Gene3D; 2.170.190.11; Molybdopterin biosynthesis moea protein, domain 3; 1.
DR   InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR   InterPro; IPR001453; MoaB/Mog_dom.
DR   InterPro; IPR008284; MoCF_biosynth_CS.
DR   InterPro; IPR038987; MoeA-like.
DR   InterPro; IPR005111; MoeA_C_domain_IV.
DR   InterPro; IPR036688; MoeA_C_domain_IV_sf.
DR   InterPro; IPR005110; MoeA_linker/N.
DR   InterPro; IPR036135; MoeA_linker/N_sf.
DR   InterPro; IPR024370; PBP_domain.
DR   NCBIfam; TIGR00177; molyb_syn; 1.
DR   PANTHER; PTHR10192:SF5; GEPHYRIN; 1.
DR   PANTHER; PTHR10192; MOLYBDOPTERIN BIOSYNTHESIS PROTEIN; 1.
DR   Pfam; PF00994; MoCF_biosynth; 1.
DR   Pfam; PF03454; MoeA_C; 1.
DR   Pfam; PF03453; MoeA_N; 1.
DR   Pfam; PF12727; PBP_like; 1.
DR   SMART; SM00852; MoCF_biosynth; 1.
DR   SUPFAM; SSF63867; MoeA C-terminal domain-like; 1.
DR   SUPFAM; SSF63882; MoeA N-terminal region -like; 1.
DR   SUPFAM; SSF53218; Molybdenum cofactor biosynthesis proteins; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   PROSITE; PS01079; MOCF_BIOSYNTHESIS_2; 1.
PE   4: Predicted;
KW   Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150}.
FT   DOMAIN          201..349
FT                   /note="MoaB/Mog"
FT                   /evidence="ECO:0000259|SMART:SM00852"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   665 AA;  69767 MW;  8A659428C0EBC917 CRC64;
     MSDRKEFRDL ATPEAAREAI DSLDLSPAPE TVPLENARGR VLSERIDAAI DVPGFDRASM
     DGYAVRARDT FGADEADPAE LDLVGAVHAG ATPEVTVEPG TCAEISTGAV MPDGADAVVM
     VERTDELDGE GGDLNAEGDA PDRIAIRTAV APGDHVMSAG ADIAAGARAL GPGTRLTPRE
     IGLLSALGVD EVPVAGTPRV GIVSTGDELV RPGDELDPSR GEIYDVNSTT IAAGVEEAGG
     EPVLYPHAGD DYDEMERLLR RAADECDLVL SSGSTSASAV DVIYRVIEER GDLLLHGVAV
     KPGKPMLVGR LDRREDADAP GPSAYIGLPG YPVSALTIFR TFVAPAIREA AGQPEPATAT
     VEGRMAVGER YGEGRMRLMP VGLLDLDDGD RPLAYPVDKG SGATTSLVEA DGVVAVDPDT
     EYLDRGERVS VQLFSPDVRP PTLLGVGEDD PALNRLLDRL ESPRYLPVGS REGLRRLRDG
     VPDAAVVAGP TDREVDAAYL GGWTREWGLV VPGGNPDGVT GLADLVDGDV RFVNRPTDSG
     LRRSLDDALD DLAADRDASR RDLADRIDGY ELTVRAFESP VRKVLAGDAD AGLGLRETAE
     RLGCGFVSLG EQSVSVRAAP DRVERDAVAE LAGALDDLDD AADGGGKPDL LADLAGYSRN
     SRNDP
//