ID M0NY48_9EURY Unreviewed; 960 AA.
AC M0NY48;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Putative PAS/PAC sensor protein {ECO:0000313|EMBL:EMA62852.1};
GN ORFNames=C469_03997 {ECO:0000313|EMBL:EMA62852.1};
OS Halorubrum lipolyticum DSM 21995.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1227482 {ECO:0000313|EMBL:EMA62852.1, ECO:0000313|Proteomes:UP000011650};
RN [1] {ECO:0000313|EMBL:EMA62852.1, ECO:0000313|Proteomes:UP000011650}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21995 {ECO:0000313|EMBL:EMA62852.1,
RC ECO:0000313|Proteomes:UP000011650};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA62852.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOJG01000010; EMA62852.1; -; Genomic_DNA.
DR RefSeq; WP_008004052.1; NZ_AOJG01000010.1.
DR AlphaFoldDB; M0NY48; -.
DR STRING; 1227482.C469_03997; -.
DR PATRIC; fig|1227482.3.peg.801; -.
DR OrthoDB; 165911at2157; -.
DR Proteomes; UP000011650; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00156; REC; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR007050; HTH_bacterioopsin.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR Pfam; PF15915; BAT; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF04967; HTH_10; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Transcription {ECO:0000256|ARBA:ARBA00023015};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 12..127
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 217..272
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 273..315
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT MOD_RES 62
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 960 AA; 104872 MW; D36A8007C4121927 CRC64;
MSSASNSALD TAAVVVVGET TWTTAYADAL RERSDATVHA VSTASAALDA LRGSGVDCVV
TDSGLPETTG VDLVRRIRDR TVALPVILGT AEGSEAIASE AIDAGVTDYV AVGDIEAAVS
DSLRRTERAI REAQRSATRR ERARQFDASF HDTRSATWVL DPDGRLTRVN RAAREMVDAD
VEVDVDAVVG DPFWTLPWWA ETDRPREDIR RLVDVARDGE FGHAVVVRDA ADERVLELSV
RPVTDERDDL VSIVVDGVDI TDRVALEREL RRSERLHRVT LNNMTDTVLM TDEGGEYTYV
CPNAHFIFGY TAEEIRELGT IEDLLGEGLF DRERLADEGV LKNIETTATD KAGREHTLLV
NVREVSIEDG TLLYSCRDVT KRKQRERALA TLQGTARDFL YAETHQEIAQ HVVDDTPGVL
GLDAGAVYLF DADDTRLRPA ARSRAMRSAH GPLPAVHADG RDLTSHSFVE DEALFLADIH
DADRLGNPAT DLRSAAYIPL GNHGVFVAGS TAVGAFDEVT RELADLLAAT AEAALDRVDR
ESQLREQDRE LQRQNDRLSA LNRINETIRE IDHGIVQSET REEIDHTVCE RLTADGRFRL
AWIGARDDTG EAVTPRAWAG TDRGYLDTQS FPVAADGVEP AGRTAATRDV THVPNVATDL
RASPWRTDAI SRDLLSALSV PLVYNDLSYG VLTVYAETPD AFDETVRTVL AELGETIAAA
ISASERKRAL LTTSMTRVEY AVRDPSFVLA RLAEVADCTL AYEGGVQQTE TGNSVFLTVE
DAPVDAVVDA TDDLVAVEAV RRIRGGDTGG VLRLRLTEPF LAAELADHGA ILRNATATSA
GTELAIDVPG GVDHRHVTQF LRERFGDVDL ASKQTREQAS EHGFYASVLD RLTDRQLEVL
ETAYYSGFFE SPRKATGETV ANSLDISPQA FYQHIRTAQR KLFTALIDDH ASVAAPHVDG
//
