ID M0PG93_9EURY Unreviewed; 334 AA.
AC M0PG93;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Cation diffusion facilitator family transporter {ECO:0000313|EMBL:EMA68923.1};
GN ORFNames=C461_04812 {ECO:0000313|EMBL:EMA68923.1};
OS Halorubrum aidingense JCM 13560.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1230454 {ECO:0000313|EMBL:EMA68923.1, ECO:0000313|Proteomes:UP000011575};
RN [1] {ECO:0000313|EMBL:EMA68923.1, ECO:0000313|Proteomes:UP000011575}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13560 {ECO:0000313|EMBL:EMA68923.1,
RC ECO:0000313|Proteomes:UP000011575};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA68923.1}.
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DR EMBL; AOJI01000017; EMA68923.1; -; Genomic_DNA.
DR RefSeq; WP_007999111.1; NZ_AOJI01000017.1.
DR AlphaFoldDB; M0PG93; -.
DR STRING; 1230454.C461_04812; -.
DR PATRIC; fig|1230454.4.peg.983; -.
DR OrthoDB; 8907at2157; -.
DR Proteomes; UP000011575; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR Gene3D; 3.30.70.1350; Cation efflux protein, cytoplasmic domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027470; Cation_efflux_CTD.
DR InterPro; IPR036837; Cation_efflux_CTD_sf.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR43840; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR PANTHER; PTHR43840:SF15; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR Pfam; PF16916; ZT_dimer; 1.
DR SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 218..290
FT /note="Cation efflux protein cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF16916"
FT REGION 290..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 334 AA; 35371 MW; 2080B65164AB0968 CRC64;
MWNPWGDGQK GRFQRVAAVN VLGNAVKIVV EGAAGLTFGS VALVADAAHS VADLVASAVV
LVWGGSRYDD ADESHPHGHQ RIEPLTALFV GATILLLGLL LFRESVAGLI GPHDVAASPI
LVAALLFAMA DMYLLYWYTD RVNASLGSTA LTALAADCLN DIYTTIAALV GVFGVFLGFP
ILDPVAGALV SVLVMYQGVE IGRENVTYLV GAAPPAGDRA RVTEALRRHP AVEGVHDLTV
YYDGTDLEVE VHVEVDGSMT LRDAHDIETE LVESLRGLDD VGDVHVHLDP SGLGEWKEAA
ERTSGGEEAR EKKEARDGEA TEQSGGPGER SDAR
//
