ID   M0PI15_9EURY            Unreviewed;       271 AA.
AC   M0PI15;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Beta-lactamase {ECO:0000313|EMBL:EMA69721.1};
GN   ORFNames=C461_02301 {ECO:0000313|EMBL:EMA69721.1};
OS   Halorubrum aidingense JCM 13560.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum.
OX   NCBI_TaxID=1230454 {ECO:0000313|EMBL:EMA69721.1, ECO:0000313|Proteomes:UP000011575};
RN   [1] {ECO:0000313|EMBL:EMA69721.1, ECO:0000313|Proteomes:UP000011575}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 13560 {ECO:0000313|EMBL:EMA69721.1,
RC   ECO:0000313|Proteomes:UP000011575};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA69721.1}.
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DR   EMBL; AOJI01000013; EMA69721.1; -; Genomic_DNA.
DR   RefSeq; WP_007998285.1; NZ_AOJI01000013.1.
DR   AlphaFoldDB; M0PI15; -.
DR   STRING; 1230454.C461_02301; -.
DR   PATRIC; fig|1230454.4.peg.475; -.
DR   OrthoDB; 6433at2157; -.
DR   Proteomes; UP000011575; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23131; ENDORIBONUCLEASE LACTB2; 1.
DR   PANTHER; PTHR23131:SF0; ENDORIBONUCLEASE LACTB2; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          20..189
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   271 AA;  27595 MW;  26B0F39FE9E664B6 CRC64;
     MSPPVTRIEV PVDTRAPGGT TNAYLADGLL VDPAARTETL DAAVGVAGAE TDVGSGAPSP
     VDAIAVTHAH PDHVGGVAAY ADLTDARVFA HAAHADRFAD ATGIEPDDTF RGGDAVGGTA
     GNTAVRAVAT PGHAPDHVAF AVGDALLCGD LAVAEGSVVV GGPGADLRAY LDSLTQVRDA
     GYGRLLPGHG PPILDPDATC QRLIDHRLDR ERAVLDAVEN GAADVDAVVD AAYEKDLAGV
     EDLARATVVA HLEKLLAVGE IGATWRDRLY D
//