ID   M0QFY9_9ACTN            Unreviewed;       403 AA.
AC   M0QFY9;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Thiamine biosynthesis oxidoreductase ThiO {ECO:0000313|EMBL:GAC67535.1};
GN   Name=thiO {ECO:0000313|EMBL:GAC67535.1};
GN   ORFNames=GS4_08_01200 {ECO:0000313|EMBL:GAC67535.1};
OS   Gordonia soli NBRC 108243.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1223545 {ECO:0000313|EMBL:GAC67535.1, ECO:0000313|Proteomes:UP000011666};
RN   [1] {ECO:0000313|EMBL:GAC67535.1, ECO:0000313|Proteomes:UP000011666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 108243 {ECO:0000313|EMBL:GAC67535.1,
RC   ECO:0000313|Proteomes:UP000011666};
RA   Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA   Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia soli NBRC 108243.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAC67535.1}.
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DR   EMBL; BANX01000008; GAC67535.1; -; Genomic_DNA.
DR   AlphaFoldDB; M0QFY9; -.
DR   STRING; 1223545.GS4_08_01200; -.
DR   eggNOG; COG0665; Bacteria.
DR   OrthoDB; 3214401at2; -.
DR   Proteomes; UP000011666; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   PANTHER; PTHR13847:SF293; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC; 1.
DR   Pfam; PF01266; DAO; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011666}.
FT   DOMAIN          25..353
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   REGION          358..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   403 AA;  42248 MW;  1ABD325A0F86529E CRC64;
     MTPGSEASTR EVPRAFPADD RRLSVVGGGV IGLTCALAAA DAGWRVTVHD AGTDRRASWV
     AGGMLGSLGE GQPGEEAALA VSVESVRRWP ALLDRLGDPS VAVARDSLFV AATSADAEYL
     DHLARFVWAR QPRAGDELQA VDARGVRTRE SALSSHVHGG YLAGGEGAID NRKLLTRLRS
     ALVEAGGRMV DERVSDLDAV DADQVLLATG LGTSALWPDA PLHAARGEIL RLTRTRWSVP
     PPASVIRARW HGRAVYLVPR EDGIVVGATQ YEPTERVVAP EAGGVADLLA DATDLMPGLR
     TYTLSEVGVG ERPCSPDGLP VIRRLDDRTV VATGHGRNGI VLAPFTADAV VDLLAGNGDA
     ATEPGSPTGS ARLTEPAHLA ETAQLMEPEQ PQPAISSRGR GAR
//