ID M0QWF3_MOUSE Unreviewed; 713 AA.
AC M0QWF3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=SANT and BTB domain regulator of CSR {ECO:0000313|Ensembl:ENSMUSP00000137799.2};
GN Name=Sanbr {ECO:0000313|Ensembl:ENSMUSP00000137799.2,
GN ECO:0000313|MGI:MGI:1918925};
GN Synonyms=0610010F05Rik {ECO:0000313|MGI:MGI:1918925};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000137799.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000137799.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000137799.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000137799.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000137799.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_006514873.1; XM_006514810.3.
DR AlphaFoldDB; M0QWF3; -.
DR SMR; M0QWF3; -.
DR MaxQB; M0QWF3; -.
DR ProteomicsDB; 367894; -.
DR Antibodypedia; 30587; 70 antibodies from 13 providers.
DR Ensembl; ENSMUST00000155903.8; ENSMUSP00000137799.2; ENSMUSG00000042208.16.
DR AGR; MGI:1918925; -.
DR MGI; MGI:1918925; Sanbr.
DR VEuPathDB; HostDB:ENSMUSG00000042208; -.
DR GeneTree; ENSGT00390000008178; -.
DR OrthoDB; 50527at2759; -.
DR BioGRID-ORCS; 71675; 3 hits in 77 CRISPR screens.
DR ChiTaRS; 0610010F05Rik; mouse.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000042208; Expressed in trigeminal ganglion and 237 other cell types or tissues.
DR ExpressionAtlas; M0QWF3; baseline and differential.
DR CDD; cd00167; SANT; 1.
DR InterPro; IPR045902; SANBR-like.
DR InterPro; IPR021777; SANBR_BTB.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR20946:SF0; SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION; 1.
DR PANTHER; PTHR20946; UNCHARACTERIZED; 1.
DR Pfam; PF11822; SANBR_BTB; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:M0QWF3,
KW ECO:0007829|ProteomicsDB:M0QWF3};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 147..248
FT /note="SANT and BTB"
FT /evidence="ECO:0000259|Pfam:PF11822"
FT REGION 555..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 713 AA; 81509 MW; 58CFA1D9F64B9DA6 CRC64;
MSRGYPENNN FLNNNNQMVL DMILYPLIGI PQTINWETVA RLVPGLTPKE CVKRFDELKS
CGSSPVDNQY NPLMATGEGP VETLATYIKS SLLDTQGDFQ ETPVDQDTVS KAGRHSIATT
RNCSSESENC TARNAGEETG ESEGPNMVIH VCDEAKSLKE DFICPRDLLI SEMKYFAEYL
SMDAQRWEEV DISVHCDVHI FNWLIKYVKR NTKESKDCEI PALEPGNVIS ILISSEFLKM
DSLVEQCIQY CHKNMNAIVA APCNMNCINA NLLTRIADLF THNEIDDLKD KKDKFRSKLF
CKKIERLFDP EYSNPDSRNN AATLYRCCLC KKLLTRETER RIPCIPGKIN VDRHGNIIYI
HIRDKTWDVH EYLNSLFEEL KSWRDVYWRL WGTVNWLTCS RCYQAFLCIE FSHCQYHSEV
VVYSSTVNSL NTVGTGIYPC CNQKVLRFDP TQLTKGCKVR DHMVVLHDQG ENDDSPSCPP
AKILDDLHKH KDVIAVPFLK DAVSDPGVGS CDEKGLEYEI LLEPNTPWGS KTGELNAFLS
LKNWTLQLKQ QSLFSEEEEY TTGSEVTEDE VGDEEEIAKK QRKKEKPKKF TKPPKKQLSS
PCSQKKEKTL EKSTSRDVSP FVVSMQKNKW DASRSLRFNQ DAQREDDQRR MSEITGHLIK
MRLGDLDRVK AKESKEFAGG IYSRLEAQVR ASVPVTARQN SSDKNQRMTS LRP
//
