ID M0QX88_HUMAN Unreviewed; 177 AA.
AC M0QX88;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=VRK serine/threonine kinase 3 {ECO:0000313|Ensembl:ENSP00000468979.1};
DE Flags: Fragment;
GN Name=VRK3 {ECO:0000313|Ensembl:ENSP00000468979.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000468979.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000468979.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0007829|PubMed:21406692}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21406692; DOI=10.1126/scisignal.2001570;
RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T.,
RA Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.;
RT "System-wide temporal characterization of the proteome and phosphoproteome
RT of human embryonic stem cell differentiation.";
RL Sci. Signal. 4:RS3-RS3(2011).
RN [3] {ECO:0000313|Ensembl:ENSP00000468979.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC011452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M0QX88; -.
DR SMR; M0QX88; -.
DR MassIVE; M0QX88; -.
DR PeptideAtlas; M0QX88; -.
DR Antibodypedia; 18806; 112 antibodies from 26 providers.
DR Ensembl; ENST00000600137.5; ENSP00000468979.1; ENSG00000105053.11.
DR UCSC; uc061boe.1; human.
DR HGNC; HGNC:18996; VRK3.
DR VEuPathDB; HostDB:ENSG00000105053; -.
DR GeneTree; ENSGT00940000158111; -.
DR ChiTaRS; VRK3; human.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000105053; Expressed in sperm and 192 other cell types or tissues.
DR ExpressionAtlas; M0QX88; baseline and differential.
DR InterPro; IPR026870; Zinc_ribbon_dom.
DR Pfam; PF13240; zinc_ribbon_2; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:M0QX88,
KW ECO:0007829|MaxQB:M0QX88};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 4..26
FT /note="Zinc-ribbon"
FT /evidence="ECO:0000259|Pfam:PF13240"
FT REGION 39..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 177
FT /evidence="ECO:0000313|Ensembl:ENSP00000468979.1"
SQ SEQUENCE 177 AA; 19367 MW; A80113A510409904 CRC64;
MISFCPDCGK SIQAAFKFCP YCGNSLPVEE HVGSQTFVNP HVSSFQGSGS RPPTPKSSPQ
KTRKSPQVTR GSPQKTSCSP QKTRQSPQTL KRSRVTTSLE ALPTGTVLTD KSGRQWKLKS
FQTRDNQGIL YEAAPTSTLT CDSGPQKQKF SLKLSTSGRS CTRPHCWPSL PAWVSVF
//
