ID M0R103_HUMAN Unreviewed; 453 AA.
AC M0R103;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Radial spoke head 6 homolog A {ECO:0000313|Ensembl:ENSP00000471559.1};
GN Name=RSPH6A {ECO:0000313|Ensembl:ENSP00000471559.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000471559.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000471559.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000471559.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC011530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC092301; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M0R103; -.
DR SMR; M0R103; -.
DR MassIVE; M0R103; -.
DR PeptideAtlas; M0R103; -.
DR Antibodypedia; 49254; 48 antibodies from 12 providers.
DR Ensembl; ENST00000600188.5; ENSP00000471559.1; ENSG00000104941.8.
DR UCSC; uc002pdl.4; human.
DR HGNC; HGNC:14241; RSPH6A.
DR VEuPathDB; HostDB:ENSG00000104941; -.
DR GeneTree; ENSGT00500000044869; -.
DR HOGENOM; CLU_021526_2_1_1; -.
DR OMA; WTFRKAY; -.
DR ChiTaRS; RSPH6A; human.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000104941; Expressed in left testis and 27 other cell types or tissues.
DR ExpressionAtlas; M0R103; baseline and differential.
DR GO; GO:0001534; C:radial spoke; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:InterPro.
DR GO; GO:0060294; P:cilium movement involved in cell motility; IEA:InterPro.
DR InterPro; IPR006802; Radial_spoke.
DR PANTHER; PTHR13159:SF1; RADIAL SPOKE HEAD PROTEIN 6 HOMOLOG A; 1.
DR PANTHER; PTHR13159; RADIAL SPOKEHEAD-RELATED; 1.
DR Pfam; PF04712; Radial_spoke; 1.
PE 1: Evidence at protein level;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Proteomics identification {ECO:0007829|PeptideAtlas:M0R103,
KW ECO:0007829|ProteomicsDB:M0R103};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..320
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..453
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 50902 MW; 3CEC807D45652E44 CRC64;
MQPTYKMAEK QKALFTRSGG GTEGEQEMEE EVGETPVPNI METAFYFEQA GVGLSSDESF
RIFLAMKQLV EQQPIHTCRF WGKILGIKRS YLVAEVEFRE GEEEAEEEEV EEMTEGGEVM
EAHGEEEGEE DEEKAVDIVP KSVWKPPPVI PKEESRSGAN KYLYFVCNEP GLPWTRLPHV
TPAQIVNARK IKKFFTGYLD TPVVSYPPFP GNEANYLRAQ IARISAATQV SPLGFYQFSE
EEGDEEEEGG AGRDSYEENP DFEGIPVLEL VDSMANWVHH TQHILPQGRC TWVNPLQKTE
EEEDLGEEEE KADEGPEEVE QEVGPPLLTP LSEDAEIMHL APWTTRLSCS LCPQYSVAVV
RSNLWPGAYA YASGKKFENI YIGWGHKYSP ESFNPALPAP IQQEYPSGPE IMEMSDPTVE
EEQALKAAQE QALGATEEEE EGEEEEEGEE TDD
//
