ID M0WNW4_HORVV Unreviewed; 715 AA.
AC M0WNW4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0000259|PROSITE:PS50115};
OS Hordeum vulgare subsp. vulgare (Domesticated barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=112509 {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.6HG0576830.1, ECO:0000313|Proteomes:UP000011116};
RN [1] {ECO:0000313|Proteomes:UP000011116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Morex {ECO:0000313|Proteomes:UP000011116};
RX PubMed=23075845; DOI=10.1038/nature11543;
RG The International Barley Genome Sequencing Consortium;
RA Mayer K.F., Waugh R., Brown J.W., Schulman A., Langridge P., Platzer M.,
RA Fincher G.B., Muehlbauer G.J., Sato K., Close T.J., Wise R.P., Stein N.;
RT "A physical, genetic and functional sequence assembly of the barley
RT genome.";
RL Nature 491:711-716(2012).
RN [2] {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.6HG0576830.1}
RP IDENTIFICATION.
RC STRAIN=subsp. vulgare
RC {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.6HG0576830.1};
RG EnsemblPlants;
RL Submitted (JAN-2022) to UniProtKB.
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DR AlphaFoldDB; M0WNW4; -.
DR PaxDb; 4513-MLOC_53294-1; -.
DR EnsemblPlants; HORVU.MOREX.r3.6HG0576830.1; HORVU.MOREX.r3.6HG0576830.1; HORVU.MOREX.r3.6HG0576830.
DR EnsemblPlants; HORVU.MOREX.r3.6HG0576830.3; HORVU.MOREX.r3.6HG0576830.3; HORVU.MOREX.r3.6HG0576830.
DR EnsemblPlants; HORVU.MOREX.r3.6HG0576830.4; HORVU.MOREX.r3.6HG0576830.4; HORVU.MOREX.r3.6HG0576830.
DR Gramene; HORVU.MOREX.r2.6HG0478350.1; HORVU.MOREX.r2.6HG0478350.1; HORVU.MOREX.r2.6HG0478350.
DR Gramene; HORVU.MOREX.r3.6HG0576830.1; HORVU.MOREX.r3.6HG0576830.1; HORVU.MOREX.r3.6HG0576830.
DR Gramene; HORVU.MOREX.r3.6HG0576830.3; HORVU.MOREX.r3.6HG0576830.3; HORVU.MOREX.r3.6HG0576830.
DR Gramene; HORVU.MOREX.r3.6HG0576830.4; HORVU.MOREX.r3.6HG0576830.4; HORVU.MOREX.r3.6HG0576830.
DR OrthoDB; 5484367at2759; -.
DR Proteomes; UP000011116; Chromosome 6H.
DR ExpressionAtlas; M0WNW4; baseline and differential.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd08838; ArfGap_AGFG; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR044820; AGD14-like.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46085:SF3; ARF-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46085; ARFGAP/RECO-RELATED; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000011116};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 12..130
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 123..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..285
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 77420 MW; EC9BF17A6876221C CRC64;
MASRVKEDEK NERVIRGLLK LPANKRCINC NNLGPQYVCT NFWTFVCTNC SGAHREFTHR
VKSVSMAKFT AQEVTALQGG GNERAREIFF KEWDSQRNPY PDSSNTDKLR NFIKYVYVER
RYTGERSSDR PPRGKDDKDE HSENRRSDGN RGGSRSPPYN ESYSDRRSYS GRSDDRNSRH
SYGERSPGYD QNDYKKSPRH FEVVDDRSGK TTPVQRFEDR RFSEPRKPET GSPNYQREAN
GSSPPVVRPV REILGDDAPQ LRIGEPPKPN VARPIDPPKP NGARTIEPPP QAQRTATASS
IGSSEGISEQ TKAVTPVSLI DFGADPEPTA SALPSQTAPT PQQQSVNAQP INTTAPQHVL
EQGRSAPSVS GGDWASFDAF GQQQQTPQSG STVNPLESVL AQLSFSETPS ASSTSAFSTS
VDQQANGGQS SMIDPSHSSL FGPPVGISGN QASTGMPVQG SAVHQSAVAA PMGGLPSLLP
SNSQGTSGIQ EATSSHDSKS SGRTALPVDF FTSLYPSATP AMPGWQRAPQ SGMGFGMQYP
AGMLQGMQSY PQAAFSQPTY QQPTYQQPMY QQPTYQQPTY QQPVYQQNAY PQPAKASNPF
DLGNEAAPIQ AHMQSLSGPL GASAGAANPT LVGNSSFGVP PQQPQQMYQP PVHQNHYMMQ
HVSNNMPEQL PNGMLPRQQG GAGSLGVGYD QQAAPRYSQP STPPSYGAVG GNPFG
//
