ID M0ZIA1_SOLTU Unreviewed; 285 AA.
AC M0ZIA1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Homeobox-leucine zipper protein {ECO:0000256|RuleBase:RU369038};
DE AltName: Full=HD-ZIP protein {ECO:0000256|RuleBase:RU369038};
DE AltName: Full=Homeodomain transcription factor {ECO:0000256|RuleBase:RU369038};
GN Name=102587525 {ECO:0000313|EnsemblPlants:PGSC0003DMT400001322};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400001322, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400001322}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400001322};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: Transcription factor. {ECO:0000256|RuleBase:RU369038}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC {ECO:0000256|ARBA:ARBA00025748, ECO:0000256|RuleBase:RU369038}.
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DR RefSeq; XP_006338548.1; XM_006338486.2.
DR AlphaFoldDB; M0ZIA1; -.
DR SMR; M0ZIA1; -.
DR PaxDb; 4113-PGSC0003DMT400001322; -.
DR EnsemblPlants; PGSC0003DMT400001322; PGSC0003DMT400001322; PGSC0003DMG400000498.
DR GeneID; 102587525; -.
DR Gramene; PGSC0003DMT400001322; PGSC0003DMT400001322; PGSC0003DMG400000498.
DR KEGG; sot:102587525; -.
DR eggNOG; KOG0483; Eukaryota.
DR HOGENOM; CLU_060842_2_0_1; -.
DR InParanoid; M0ZIA1; -.
DR OMA; GSCHGYF; -.
DR OrthoDB; 3042435at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M0ZIA1; baseline.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:UniProtKB-UniRule.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:EnsemblPlants.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009965; P:leaf morphogenesis; IEA:EnsemblPlants.
DR GO; GO:0017148; P:negative regulation of translation; IEA:EnsemblPlants.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IBA:GO_Central.
DR GO; GO:0009637; P:response to blue light; IEA:EnsemblPlants.
DR GO; GO:0009651; P:response to salt stress; IEA:EnsemblPlants.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR045224; HDZip_class_I_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR InterPro; IPR003106; Leu_zip_homeo.
DR PANTHER; PTHR24326; HOMEOBOX-LEUCINE ZIPPER PROTEIN; 1.
DR PANTHER; PTHR24326:SF497; HOMEOBOX-LEUCINE ZIPPER PROTEIN HAT5; 1.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Transcription {ECO:0000256|RuleBase:RU369038};
KW Transcription regulation {ECO:0000256|RuleBase:RU369038}.
FT DOMAIN 61..121
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 63..122
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 37..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 113..161
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 37..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 32221 MW; 9375410CF2F9C922 CRC64;
MGSGHIFFDP SSCHGNMLFL GNGDPVFRGP RSTMMKMEDS SKRRPFFSSP EDLYDEDYYD
EQSPEKKRRL TPEQVHLLEK SFETENKLEP ERKTQLAKKL GLQPRQVAVW FQNRRARWKT
KQLERDYDQL KSSYDSLLSD FDSIRKDNDK LKSEVVSLME KLQGKVVGGA GVSEKSDVLE
VDAMTATLQV KVKAEDRLSS GSGGSAVVDE HSPQLVDSGD SYFHTDHEEY PGPGGCNVPP
HMDGLQSEED DGSDDGSCHG YFSNVFVTEV QHHEEGEEPI GWFWS
//
