ID M0ZSI6_SOLTU Unreviewed; 369 AA.
AC M0ZSI6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Solute carrier family 40 member {ECO:0000256|RuleBase:RU365065};
GN Name=102582045 {ECO:0000313|EnsemblPlants:PGSC0003DMT400007139};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400007139, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400007139}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400007139};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: May be involved in iron transport and iron homeostasis.
CC {ECO:0000256|RuleBase:RU365065}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU365065}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365065}.
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000256|ARBA:ARBA00006279,
CC ECO:0000256|RuleBase:RU365065}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU365065}.
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DR AlphaFoldDB; M0ZSI6; -.
DR EnsemblPlants; PGSC0003DMT400007139; PGSC0003DMT400007139; PGSC0003DMG400002762.
DR Gramene; PGSC0003DMT400007139; PGSC0003DMT400007139; PGSC0003DMG400002762.
DR Gramene; RHC01H1G3728.2.1; RHC01H1G3728.2.1; RHC01H1G3728.2.
DR HOGENOM; CLU_033119_1_0_1; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M0ZSI6; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11660; SOLUTE CARRIER FAMILY 40 MEMBER; 1.
DR PANTHER; PTHR11660:SF53; SOLUTE CARRIER FAMILY 40 MEMBER 3, CHLOROPLASTIC; 1.
DR Pfam; PF06963; FPN1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU365065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365065};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365065};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365065};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365065}.
FT TRANSMEM 25..47
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 68..89
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 174..196
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 202..223
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 235..255
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 261..278
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 299..324
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 330..351
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
SQ SEQUENCE 369 AA; 39040 MW; 1055E43BD686BE0B CRC64;
MSVGMIIHGH TLHPTSASSL LFRPWFIVLV LVGAVERLSG LALGVAVERD WIVLLAGTNR
PVALAQANAV LSRINLLCEI VGAALFGILL SKYELVVCLK IAAGLMMGAL PIVVSLTWLT
NKLSSGVLDR AVETCLSCSF PSSLKSENIV GVGLEAIKHG WFEYIRQPVL PASIAYVLLY
FNVVLAPGGL MTAFLTQQGL NPSIIGGFSG LCAFVGVAAT FVSAKMVKHL GILKAGAAGL
VFHASLLTTA VAVYWSGCLS QQTPIFFFLA LVVLSRLGHM SYDVIGQQIL QTGIPASKAN
LIGTTEVSVA SLAESIMLGV AIVVNDVSHF GFLATLSLVS VVGAACLYCR WLENPTDTQR
TLFSFSPHL
//
